Ravindra Krishna, Vanchiere Catherine, Ferrari Victor A
Department of Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Division of Cardiovascular Medicine and Cardiovascular Institute, Hospital of the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania Philadelphia, Pennsylvania, USA.
JACC Case Rep. 2025 Jun 25;30(16):103802. doi: 10.1016/j.jaccas.2025.103802. Epub 2025 Mar 24.
This clinical vignette highlights the use of echocardiography, computed tomography, positron emission tomography, magnetic resonance imaging, and invasive hemodynamics to aid in making a rare diagnosis. This case highlights a 62-year-old male who presented with worsening dyspnea and was ultimately found to have constrictive pericarditis secondary to primary pericardial mesothelioma. The use of multimodality imaging can facilitate early diagnosis of this rare condition, helping to initiate treatment options for an otherwise high-mortality disease.
这个临床案例突出了超声心动图、计算机断层扫描、正电子发射断层扫描、磁共振成像和有创血流动力学检查在辅助做出罕见诊断方面的应用。该病例为一名62岁男性,表现为进行性加重的呼吸困难,最终被诊断为原发性心包间皮瘤继发缩窄性心包炎。多模态成像的应用有助于对这种罕见疾病进行早期诊断,从而为这种原本死亡率很高的疾病启动治疗方案。