Yu Simin, Zhang Yue, Nie Yufan, Wang Zikang, Liu Yuping, Zhang Luyao, Liu Rui, Diao Jinling
Department of Applied Chemistry, China Agricultural University, Beijing 100193, China.
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
J Hazard Mater. 2025 Aug 15;494:138655. doi: 10.1016/j.jhazmat.2025.138655. Epub 2025 May 18.
Ectothermic reptiles, vulnerable to future warming, may adapt through maternal effects. However, the effects of glyphosate-based herbicides (GBHs) on this adaptive mechanism remain unclear. To explore, we conducted a cross-design experiment on lizards (Eremias argus) under normal and elevated temperatures, with or without GBH exposure. We assessed maternal reproductive output, egg composition, embryo hatching performance, and the morphological and performance traits of offspring which were uniformly reared under warming regime. Under warming conditions, female enhanced reproductive output by reducing relative clutch mass and increasing egg-laying frequency. They also helped offspring adapt to warmer environments via maternal resource transfer, likely by the observed increases in unsaturated fatty acids and amino acids in eggs. Hatchlings from the warming treatment groups exhibited higher survival rates, underscoring the potential of maternal effect in thermal adaptation. GBH exposure in a warming environment led to reduced reproductive frequency, lower hatching rates, smaller hatchlings and decreased offspring thermal tolerance, diminishing the benefits of maternal effect. These effects may be linked to reduced levels of nucleotide metabolism-related substances, triglycerides, proline, and citrulline in eggs. Our study revealed the adverse effects of GBH on lizards and provided new insights into the impact of chemical pollutants on biological adaptability in the context of climate change.
变温爬行动物易受未来气候变暖的影响，可能会通过母体效应来适应。然而，基于草甘膦的除草剂（GBHs）对这种适应机制的影响仍不清楚。为了进行探究，我们在正常温度和高温条件下，对蜥蜴（丽斑麻蜥）进行了一项交叉设计实验，实验中蜥蜴暴露或未暴露于GBHs。我们评估了母体的繁殖产出、卵的成分、胚胎孵化表现，以及在变暖环境下统一饲养的后代的形态和性能特征。在变暖条件下，雌性蜥蜴通过降低相对窝卵质量和增加产卵频率来提高繁殖产出。它们还可能通过观察到的卵中不饱和脂肪酸和氨基酸的增加，通过母体资源转移帮助后代适应更温暖的环境。变暖处理组的幼体表现出更高的存活率，突出了母体效应在热适应中的潜力。在变暖环境中暴露于GBHs会导致繁殖频率降低、孵化率降低、幼体变小以及后代耐热性下降，从而削弱母体效应的益处。这些影响可能与卵中核苷酸代谢相关物质、甘油三酯、脯氨酸和瓜氨酸水平的降低有关。我们的研究揭示了GBHs对蜥蜴的不利影响，并为在气候变化背景下化学污染物对生物适应性的影响提供了新的见解。
