de Graeff Nienke, De Proost Lien
Department of Medical Ethics and Health Law, Leiden University Medical Center, Leiden, The Netherlands
Department of Medical Ethics and Health Law, Leiden University Medical Center, Leiden, The Netherlands.
J Med Ethics. 2025 May 19. doi: 10.1136/jme-2025-110866.
Gyngell argue that no intrinsic differences exist between stem cell-derived embryo models (SCEMs) and embryos derived from fertilisation that would justify attributing a higher moral status to the latter. Consequently, they claim there is no ethical rationale for treating SCEMs differently from embryos and contend that endorsing SCEMs as having moral advantages over embryos constitutes an obfuscation. In this commentary, we challenge the assertion that human SCEMs and embryos are morally equivalent by painting a more nuanced picture of the moral value of (different kinds of) SCEMs and embryos. First, we highlight the diversity among SCEMs, noting that different types of SCEMs need not be morally equivalent. This point is illustrated by taking a closer look at their potentiality, a property often considered relevant to moral status. Second, we observe that Gyngell , like much of the broader debate, primarily concentrate on the direct moral status of SCEMs in their analysis of the moral (in)equivalence with embryos. We argue that a comprehensive moral evaluation should encompass different types of moral value, evaluating not only direct moral status but also relational, symbolic and instrumental value. Ultimately, we suggest that the real obfuscation lies not in endorsing SCEMs as having moral advantages over embryos but rather in the overemphasis on direct moral status and the binary thinking about the moral (in)equivalence of embryos versus SCEMs that dominates these discussions.
金盖尔认为,干细胞衍生胚胎模型(SCEMs)与受精衍生胚胎之间不存在内在差异,这使得赋予后者更高的道德地位缺乏正当理由。因此,他们声称,没有伦理依据将SCEMs与胚胎区别对待,并认为支持SCEMs比胚胎具有道德优势是一种混淆视听的行为。在这篇评论中,我们通过对(不同类型的)SCEMs和胚胎的道德价值描绘出一幅更细致入微的图景,来质疑人类SCEMs和胚胎在道德上等同的断言。首先,我们强调SCEMs之间的多样性,指出不同类型的SCEMs在道德上不一定等同。通过仔细审视它们的潜能(一种常被认为与道德地位相关的属性)可以说明这一点。其次,我们注意到,与更广泛的辩论中的许多情况一样,金盖尔在分析与胚胎的道德(不)等同性时,主要关注SCEMs的直接道德地位。我们认为,全面的道德评估应涵盖不同类型的道德价值,不仅要评估直接道德地位,还要评估关系性、象征性和工具性价值。最终,我们认为真正的混淆不在于支持SCEMs比胚胎具有道德优势,而在于过度强调直接道德地位以及在这些讨论中占主导地位的关于胚胎与SCEMs道德(不)等同性的二元思维。