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美国女性退伍军人中军事性创伤与下尿路症状(LUTS)及大便失禁(FI)的关联

Military Sexual Trauma's Association with Lower Urinary Tract Symptoms (LUTS) and Fecal Incontinence (FI) Among U.S. Female Veterans.

作者信息

Roberts Brittany, Neumann Alexandra, Shenk Chloe, Rogers Rebecca, Wolff Gillian

机构信息

Department of Obstetrics and Gynecology, Albany Medical Center, Division of Urogynecology, Albany, New York, USA.

McGill University, Montreal, Quebec, Canada.

出版信息

J Trauma Dissociation. 2025 Jul-Sep;26(4):524-533. doi: 10.1080/15299732.2025.2503714. Epub 2025 May 21.

Abstract

IMPORTANCE

Military Sexual Trauma (MST) affects a large number of female veterans and is associated with various adverse physical and mental health conditions. Sexual trauma can lead to pelvic floor dysfunction, contributing to lower urinary tract symptoms (LUTS), a common urological concern, and fecal incontinence (FI). LUTS and FI may have a higher prevalence among female veterans with MST.

OBJECTIVES

This study aimed to evaluate the prevalence and treatment of LUTS/FI among female veterans with a history of MST compared to those without.

STUDY DESIGN

A retrospective cohort analysis was conducted using data from the Veterans Health Administration's (VHA) Corporate Data Warehouse. Baseline demographic data, International Classification of Diseases (ICD-9) codes, and medication use were analyzed, with logistic regression models controlling for confounders.

RESULTS

Of the 416,137 female veterans analyzed, 103,877 (25%) reported a history of MST. Veterans with MST were more likely to be diagnosed with LUTS and FI, including a 22% (aOR 1.215; 95% CI 1.133, 1.302) increase in voiding issues and 17% (aOR 1.163; 95% CI 1.132, 1.194) increase in storage difficulties; 26% (aOR 1.260; 95% CI 1.136, 1.397) increase in interstitial cystitis/bladder pain syndrome (IC/BPS), and 34% (aOR 1.338; 95% CI 1.224,1.462) increase in FI. MST was associated with increased odds of undergoing diagnostic procedures for LUTS, such as cystoscopy (aOR 1.221; 95% CI 1.159, 1.287) and urodynamics (aOR 1.241; 95% CI 1.158,1.331). Veterans with MST were 15% more likely to receive pharmacological treatment for overactive bladder (aOR 1.152; 95% CI 1.122, 1.182).

CONCLUSIONS

Female veterans with MST have a higher prevalence of LUTS and FI and are more likely to undergo diagnostic and therapeutic interventions.

摘要

重要性

军事性创伤(MST)影响着大量女性退伍军人,并与各种不良身心健康状况相关。性创伤可导致盆底功能障碍,进而引发下尿路症状(LUTS),这是一种常见的泌尿系统问题,还会导致大便失禁(FI)。在有MST病史的女性退伍军人中,LUTS和FI的患病率可能更高。

目的

本研究旨在评估有MST病史的女性退伍军人与无此病史的女性退伍军人相比,LUTS/FI的患病率及治疗情况。

研究设计

使用退伍军人健康管理局(VHA)企业数据仓库的数据进行回顾性队列分析。分析了基线人口统计学数据、国际疾病分类(ICD - 9)编码和用药情况,并采用逻辑回归模型控制混杂因素。

结果

在分析的416,137名女性退伍军人中,103,877名(25%)报告有MST病史。有MST的退伍军人更有可能被诊断为LUTS和FI,包括排尿问题增加22%(调整后比值比[aOR] 1.215;95%置信区间[CI] 1.133,1.302),储尿困难增加17%(aOR 1.163;95% CI 1.132,1.194);间质性膀胱炎/膀胱疼痛综合征(IC/BPS)增加26%(aOR 1.260;95% CI 1.136,1.397),FI增加34%(aOR 1.338;95% CI 1.224,1.462)。MST与接受LUTS诊断程序(如膀胱镜检查[aOR 1.221;95% CI 1.159,1.287]和尿动力学检查[aOR 1.241;95% CI 1.158,1.331])的几率增加相关。有MST的退伍军人接受膀胱过度活动症药物治疗的可能性高15%(aOR 1.152;95% CI 1.122,1.182)。

结论

有MST病史的女性退伍军人中LUTS和FI的患病率更高,且更有可能接受诊断和治疗干预。

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