Ju Shan, Kang Zhen Yang, Yang Li Ya, Xia Yong Jun, Guo Yi Ming, Li Sui, Yan Hongli, Qi Ming Kang, Wang Hui Ping, Zhong Lian
School of Health Science and Engineering, Shanghai Engineering Research Center of Food Microbiology, University of Shanghai for Science and Technology, Shanghai, 200093, PR China.
Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100730, China.
J Ovarian Res. 2025 May 21;18(1):105. doi: 10.1186/s13048-025-01684-5.
The gut microbiota is a complex community of microorganisms that inhabit the human gastrointestinal tract, helping to maintain the ecological balance of the body's internal and external environments. Disruptions in the composition and diversity of gut microbiota, as well as changes in their metabolic functions, can link to the development and severity of conditions such as premature ovarian insufficiency, polycystic ovary syndrome, and ovarian tumors. This article thoroughly reviews recent research on the connection between gut microbiota and ovarian diseases, providing fresh perspectives on their prevention, pathogenesis, and treatment.
肠道微生物群是栖息在人类胃肠道中的复杂微生物群落，有助于维持人体内外环境的生态平衡。肠道微生物群的组成和多样性的破坏以及它们代谢功能的变化，可能与卵巢早衰、多囊卵巢综合征和卵巢肿瘤等疾病的发生和严重程度有关。本文全面综述了肠道微生物群与卵巢疾病之间联系的最新研究，为它们的预防、发病机制和治疗提供了新的视角。
