日粮中链脂肪酸添加水平对保育猪生长性能、血液参数、粪便评分和代谢产物的影响。

Effects of dietary medium-chain fatty acid supplementation levels on growth performance, blood parameters, fecal score and metabolites in nursery pigs.

作者信息

Kwon Chan Ho, Torres Jannell A, Mejia Madison J, Safaie Eva S, Usack Joseph G, Jang Young Dal

机构信息

Department of Animal and Dairy Science, University of Georgia, Athens, GA, USA.

Department of Food Science and Technology, University of Georgia, Athens, GA, USA.

出版信息

Anim Biosci. 2025 Oct;38(10):2173-2184. doi: 10.5713/ab.25.0099. Epub 2025 May 19.

DOI:10.5713/ab.25.0099

PMID:40400192

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12415358/

Abstract

OBJECTIVE

This study evaluated the effects of increasing medium-chain fatty acid (MCFA) supplementation levels on growth performance, blood parameters, fecal score, and metabolites in nursery pigs.

METHODS

A total of 100 newly weaned pigs (initial body weight: 6.68±0.97 kg) were allotted to 5 treatments in 5 replicates, with 4 pigs per pen for a 28-d feeding trial. Treatments were MCFA supplementation levels at 0.0%, 0.4%, 0.8%, 1.2%, and 1.6%. The 2% soybean oil in the basal diet was replaced with MCFA (a 50:50 blend of free caproic and caprylic acids) on a weight-to-weight basis.

RESULTS

Increasing MCFA levels tended to linearly increase the final body weight (p = 0.06) and average daily gain in the overall period (p = 0.06), with no difference in overall average daily feed intake. The gain-to-feed ratio increased linearly in d 7-14 (p = 0.06, tendency) and 14-21 postweaning (p<0.05). Fecal score linearly decreased in d 0-7, 7-14, and 14-21 (p<0.05) postweaning, resulting in a linear reduction in the overall period (p<0.05). Plasma malondialdehyde levels at d 28 postweaning showed a quadratic decrease with increasing MCFA levels with the lowest value at 0.8% (p<0.05). Plasma free fatty acid levels at d 14 postweaning linearly decreased with increasing MCFA levels (p<0.05). Fecal total short-chain fatty acid (SCFA) concentrations tended to be lower (p = 0.09, tendency) in the MCFA treatments (0.4%-1.6%) than the control treatment (0.0%). There were no differences in plasma superoxide dismutase activity and fecal ammonia concentrations among dietary treatments.

CONCLUSION

Increasing MCFA supplementation levels up to 1.6% could improve growth rate, feed efficiency, and fecal consistency without affecting feed intake and have the potential to reduce oxidative stress and free fatty acid levels in weaning pigs, while fecal SCFA concentrations could be slightly reduced by MCFA supplementation.

摘要

目的

本研究评估了提高中链脂肪酸（MCFA）添加水平对保育猪生长性能、血液参数、粪便评分和代谢产物的影响。

方法

将100头刚断奶的仔猪（初始体重：6.68±0.97千克）分配到5个处理组，每组5个重复，每栏4头猪，进行为期28天的饲养试验。处理组的MCFA添加水平分别为0.0%、0.4%、0.8%、1.2%和1.6%。基础日粮中2%的大豆油按重量比被MCFA（己酸和辛酸50:50的混合物）替代。

结果

提高MCFA水平有使最终体重（p = 0.06）和整个试验期平均日增重呈线性增加的趋势（p = 0.06），而整个试验期的平均日采食量无差异。在断奶后第7 - 14天（p = 0.06，趋势）和14 - 21天（p<0.05），料重比呈线性增加。断奶后第0 - 7天、7 - 14天和14 - 21天粪便评分呈线性下降（p<0.05），导致整个试验期线性降低（p<0.05）。断奶后第28天血浆丙二醛水平随着MCFA水平的增加呈二次下降，在0.8%时最低（p<0.05）。断奶后第14天血浆游离脂肪酸水平随着MCFA水平的增加呈线性下降（p<0.05）。MCFA处理组（0.4% - 1.6%）的粪便总短链脂肪酸（SCFA）浓度比对照组（0.0%）有降低的趋势（p = 0.09，趋势）。各日粮处理组间血浆超氧化物歧化酶活性和粪便氨浓度无差异。