Erich W B, Peltenburg A L, Minkhorst J, VanDessel B, Bernink M J, Biersteker-Hubben M W, Zonderland M L, Huisveld I A
Growth. 1985 Spring;49(1):131-40.
This investigation deals with the influence of physical activity on the growth and sexual maturation of weanling female Wistar rats. It involves three groups of rats, namely an intensively trained group (n = 45), a moderately trained group (n = 49) and a nontrained group (n = 49). The trained groups were forced to perform physical exercise from the age of 15 days on, on a treadmill. Within the intensively trained group, exercise was increased by increasing the speed and grade of the treadmill. The exercise of the moderately trained group was held constant. A delay in the day at vulva opening, indicating sexual maturation is seen in the extensively trained group in comparison with the moderately trained and nontrained group. The average body weight at the day of vulva opening is the same in all groups. However, the correlation coefficient between day at vulva opening and body fat mass is not significant. No differences in the body- and tail-length growth can be detected between the groups. A delay in the sexual maturation due to stress can be rejected since the open fields results registrating stress parameters, as obtained from the various groups of animals, are in general not significantly different between the intensively trained and moderately trained as well as nontrained groups. This investigation shows evidence that intensive physical exercise from young age on, causes a delay in sexual maturation, although it has no influence on the body- and tail length growth.
本研究探讨体育活动对断乳期雌性Wistar大鼠生长和性成熟的影响。研究涉及三组大鼠，即高强度训练组（n = 45）、中等强度训练组（n = 49）和非训练组（n = 49）。训练组从15日龄起被迫在跑步机上进行体育锻炼。在高强度训练组中，通过提高跑步机的速度和坡度来增加运动量。中等强度训练组的运动量保持不变。与中等强度训练组和非训练组相比，高强度训练组出现阴门开启日延迟，表明性成熟延迟。所有组阴门开启日的平均体重相同。然而，阴门开启日与体脂量之间的相关系数不显著。各组之间在体长和尾长生长方面未检测到差异。由于从不同组动物获得的记录应激参数的旷场实验结果在高强度训练组、中等强度训练组和非训练组之间总体上无显著差异，因此可以排除应激导致性成熟延迟的可能性。本研究表明，幼年起进行高强度体育锻炼会导致性成熟延迟，尽管对体长和尾长生长没有影响。
