Westlake Erica, Billings Katherine, McMoran Ann, Selman Katherine, Sodhi Sarab
Cooper University Hospital, Department of Emergency Medicine, Camden, New Jersey.
Inova Fairfax Hospital, Department of Emergency Medicine, Falls Church, Virgina.
Clin Pract Cases Emerg Med. 2025 May;9(2):154-156. doi: 10.5811/cpcem.33516.
Tetanus is a now rare disease due to the widespread administration of scheduled and prophylactic vaccines, making it exceptionally uncommon to appear in many emergency departments. Clinical suspicion alone is used to make the diagnosis as there are currently no immediately available diagnostic tests available to the clinician. If left unrecognized and untreated, however, tetanus can lead to airway compromise and death.
We report a case of a young male who presented to the emergency department with intermittent full body spasms and stiffness of the masseter muscles in the setting of recent assaults and lacerations weeks prior who had not received tetanus since 2008. Immediate calls were placed to infectious disease consultants and the patient was treated with intravenous immunoglobulin, tetanus immunization, metronidazole, and ceftriaxone. Further work up revealed rhabdomyolysis, elevated lactate, and unremarkable imaging.
Following treatment, the patient's symptoms improved to resolution with completion of therapy, effectively confirming the diagnosis of tetanus.
由于定期和预防性疫苗的广泛接种,破伤风现在是一种罕见疾病,在许多急诊科很少出现。由于目前临床医生没有即时可用的诊断测试,仅靠临床怀疑来做出诊断。然而,如果未被识别和治疗,破伤风可导致气道受损和死亡。
我们报告一例年轻男性病例,该患者在数周前遭受袭击和撕裂伤后,未接种破伤风疫苗(自2008年以来),因咬肌间歇性全身痉挛和僵硬而就诊于急诊科。立即致电传染病顾问,患者接受了静脉注射免疫球蛋白、破伤风免疫接种、甲硝唑和头孢曲松治疗。进一步检查发现横纹肌溶解、乳酸升高,影像学检查无异常。
经过治疗,患者症状在治疗结束时改善至痊愈,有效确诊为破伤风。