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破伤风:一例病例报告、流行病学综述及免疫接种依从性建议

Tetanus: a case report, epidemiology review and recommendations for immunization compliance.

作者信息

Cannarella R, Agbayani E

机构信息

Harpers Ferry Family Medicine, Harpers Ferry, West Virginia University School of Medicine, Harpers Ferry Branch, West Virginia University Family Practice Rural Residency Program, Harpers Ferry, USA.

出版信息

W V Med J. 2001 Sep-Oct;97(5):253-6.

Abstract

Tetanus is a forgotten disease in the United States since many practicing primary care physicians have not seen a case of the disease in their career. A 73-year-old woman presented with dysphagia two weeks after she obtained a superficial laceration while gardening. Within days, the jaw spasms and subsequent respiratory compromise that necessitated five weeks of ventilator support revealed the devastation that this disease can cause. Tetanus spores are found in high concentration in the soils of rural areas, especially where farm animals have grazed. Populations most at risk in the U.S. include under- or non-immunized elderly and immigrant populations. Barriers to immunization include patient and physician non-compliance, missed opportunity for immunization and concern over vaccine side effects. Targeting high-risk groups will enable primary care physicians to be more proactive in providing immunization, and thus in preventing prevention this disease.

摘要

破伤风在美国是一种被遗忘的疾病,因为许多执业初级保健医生在其职业生涯中从未见过这种疾病的病例。一名73岁的女性在园艺时出现浅表撕裂伤两周后出现吞咽困难。几天内,牙关痉挛以及随后需要五周呼吸机支持的呼吸功能不全揭示了这种疾病可能造成的破坏。破伤风孢子在农村地区的土壤中浓度很高,尤其是在农场动物放牧过的地方。美国最易感染的人群包括未接种或未完全接种疫苗的老年人和移民群体。免疫接种的障碍包括患者和医生的不依从、错过免疫接种机会以及对疫苗副作用的担忧。针对高危人群将使初级保健医生在提供免疫接种方面更加积极主动,从而预防这种疾病。

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