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U.S. Eligibility and Preventable Cardiovascular, Diabetes, and Kidney Outcomes From Semaglutide in the SELECT Trial.

作者信息

Yan Hongmei, Karthikeyan Hridhay, Fan Wenjun, Yang Qin, Wong Nathan D

机构信息

Mary and Steve Wen Cardiovascular Division, Department of Medicine, University of California, Irvine, California, USA; Division of Endocrinology, Department of Medicine, University of California, Irvine, California, USA; Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China.

Mary and Steve Wen Cardiovascular Division, Department of Medicine, University of California, Irvine, California, USA.

出版信息

JACC Adv. 2025 Jun;4(6 Pt 2):101773. doi: 10.1016/j.jacadv.2025.101773. Epub 2025 May 21.

DOI:10.1016/j.jacadv.2025.101773
PMID:40402121
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12277595/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b45/12277595/92231cba5c72/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b45/12277595/92231cba5c72/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b45/12277595/92231cba5c72/gr1.jpg

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U.S. Eligibility and Preventable Cardiovascular, Diabetes, and Kidney Outcomes From Semaglutide in the SELECT Trial.司美格鲁肽在SELECT试验中的美国适用人群及可预防的心血管、糖尿病和肾脏结局
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Eligibility for and practical implications of Semaglutide in overweight and obese patients with acute coronary syndrome.司美格鲁肽在急性冠状动脉综合征超重和肥胖患者中的适用性及实际意义。
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Semaglutide versus placebo in patients with heart failure and mildly reduced or preserved ejection fraction: a pooled analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM randomised trials.司美格鲁肽对比安慰剂在射血分数轻度降低或保留的心衰患者中的疗效:SELECT、FLOW、STEP-HFpEF 和 STEP-HFpEF DM 随机试验的汇总分析。
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Is semaglutide cost-effective at closing the gap for Aboriginal and Torres Strait Islander Australians with cardiovascular disease and obesity without type 2 diabetes?
Intern Med J. 2025 Jul 22. doi: 10.1111/imj.70160.
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Semaglutide: a key medication for managing cardiovascular-kidney-metabolic syndrome.司美格鲁肽:治疗心血管-肾脏-代谢综合征的关键药物。
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Allocation of Semaglutide According to Coronary Artery Calcium and BMI: Applying the SELECT Trial to MESA.根据冠状动脉钙化和体重指数分配司美格鲁肽:将SELECT试验应用于多族裔动脉粥样硬化研究(MESA)
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引用本文的文献

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Metabolomic profiling reveals interindividual metabolic variability and its association with cardiovascular-kidney-metabolic syndrome risk.代谢组学分析揭示个体间的代谢变异性及其与心血管-肾脏-代谢综合征风险的关联。
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本文引用的文献

1
National and State Estimates of SELECT Trial Eligibility and Its Public Health Impact in the US.美国SELECT试验资格的全国和州估计及其对公共卫生的影响。
JAMA Netw Open. 2024 Jul 1;7(7):e2420105. doi: 10.1001/jamanetworkopen.2024.20105.
2
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.司美格鲁肽在肥胖但无糖尿病患者中的心血管结局。
N Engl J Med. 2023 Dec 14;389(24):2221-2232. doi: 10.1056/NEJMoa2307563. Epub 2023 Nov 11.
3
Eligibility for Cardiovascular Risk Reduction Therapy in the United States Based on SELECT Trial Criteria: Insights From the National Health and Nutrition Examination Survey.
基于SELECT试验标准的美国心血管疾病风险降低治疗资格:来自国家健康与营养检查调查的见解
Circ Cardiovasc Qual Outcomes. 2024 Jan;17(1):e010640. doi: 10.1161/CIRCOUTCOMES.123.010640. Epub 2023 Nov 11.
4
US Population Eligibility and Estimated Impact of Semaglutide Treatment on Obesity Prevalence and Cardiovascular Disease Events.美国人群的资格以及司美格鲁肽治疗对肥胖患病率和心血管疾病事件的估计影响。
Cardiovasc Drugs Ther. 2025 Feb;39(1):75-84. doi: 10.1007/s10557-023-07488-3. Epub 2023 Aug 14.
5
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.司美格鲁肽与 2 型糖尿病患者的心血管结局
N Engl J Med. 2016 Nov 10;375(19):1834-1844. doi: 10.1056/NEJMoa1607141. Epub 2016 Sep 15.