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实施下肢动脉搭桥强化康复路径可缩短住院时间。

Implementation of enhanced recovery pathway for lower extremity arterial bypass decreases length of stay.

作者信息

Chao Calvin L, Lopes Lara, Reddy Nidhi K, El-Gabri Deena, Broucek Lauren A, Sobolewski Rebekkah B, Willens Nicole, Prochno Kyle W, Pillado Eric B, Schneider Joseph R, Wilkinson Julia B, Hoel Andrew W, Tomita Tadaki M, Vavra Ashley K

机构信息

Division of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.

Quality Department, Northwestern Memorial Hospital, Chicago, IL.

出版信息

J Vasc Surg. 2025 Sep;82(3):1014-1023.e11. doi: 10.1016/j.jvs.2025.05.023. Epub 2025 May 20.

DOI:10.1016/j.jvs.2025.05.023
PMID:40404026
Abstract

OBJECTIVE

Frailty, nutrition, and comorbid conditions are all challenges that contribute to significant morbidity in patients undergoing lower extremity arterial bypass (LEAB). Evidence supports that enhanced recovery pathways (erps) can improve perioperative outcomes. However, few studies have demonstrated successful implementation of an ERP for LEAB. The goal of this study was to demonstrate the successful implementation of an ERP in a complex patient population undergoing LEAB, including elective, urgent, or emergent procedures with the goal of decreasing length of stay (LOS) and morbidity for patients undergoing these procedures at our institution.

METHODS

Multistakeholder meetings with representatives from all vascular surgery practice sites in the Northwestern Medicine system were conducted to review current evidence-based practices and finalize an ERP for patients undergoing LEAB. Pathway elements included standardized patient education, minimal perioperative fasting with preoperative carbohydrate loading, opioid-sparing analgesia, and early postoperative diet and mobilization. The ERP was initiated in February 2022 as a pilot at a single institution. At 20 months, patient data and process and outcome measures were abstracted from the medical record and validated by four independent reviewers for univariate analysis.

RESULTS

Over the 20-month study period, 112 patients underwent LEAB. Process measures were tracked to determine compliance with the ERP. Patients had to receive >70% of the pathway elements to be considered part of the ERP (n = 60). If patients missed >30% of the elements, they were analyzed as traditional pathway (n = 52). There were no significant differences in patient demographics, body mass index, or hemoglobin a1c. ERP patients were more likely to be elective (76.7% vs 48.1%; P = .0004) and for chronic limb-threatening ischemia (76.7% vs 48.1%; P = .001) and less likely to be urgent or emergent. No significant difference was observed in frequency of infrageniculate bypass target or operative duration. Compliance with 10 perioperative process measures ranged from 28% to 98% in the ERP group. Compliance was most successful with preoperative education (81.6%), chlorhexidine wash (80.0%), postoperative mobilization (90.0%), early solid diet (98.3%), and postoperative opioid sparing strategies (98.3%). Challenges included preoperative acetaminophen (28.3%), carbohydrate load (33.8%), and postoperative protein supplementation (28.3%). Notably, ERP patients demonstrated significantly reduced total LOS (7.8 days vs 13.6 days; P = .014), postoperative LOS (6.0 days vs 11.0 days; P = .0058), and unplanned reoperations (10.0% vs 28.9%; P = .015) when compared with traditional pathway patients. ERP patients trended toward fewer unplanned readmissions (13.3% vs 26.9%; P = .095).

CONCLUSIONS

Our findings suggest that an ERP for LEAB is feasible in both elective and nonelective settings, although compliance with the ERP individual elements was more challenging for patients undergoing procedures for emergent or urgent indications. Patients undergoing ERP had improved compliance with process measures, reduced LOS, and fewer unplanned reoperations. Our results highlight the benefits of ERP for LEAB and the complex vascular surgery population and some of the potential barriers worth considering in this patient population.

摘要

目的

衰弱、营养状况和合并症都是下肢动脉搭桥术(LEAB)患者发生严重发病情况的影响因素。有证据表明,强化康复路径(ERP)可改善围手术期结局。然而,很少有研究证明成功实施了针对LEAB的ERP。本研究的目的是证明在接受LEAB的复杂患者群体中成功实施ERP,包括择期、紧急或急诊手术,目标是缩短我院接受这些手术患者的住院时间(LOS)并降低发病率。

方法

与西北医学系统中所有血管外科手术地点的代表举行多利益相关方会议,以审查当前的循证实践并确定针对接受LEAB患者的ERP。路径要素包括标准化患者教育、围手术期最短禁食时间并进行术前碳水化合物负荷补充、阿片类药物节省镇痛、术后早期饮食和活动。ERP于2022年2月在一家机构作为试点启动。在20个月时,从病历中提取患者数据以及过程和结局指标,并由四名独立审查员进行验证以进行单变量分析。

结果

在20个月的研究期间,112例患者接受了LEAB。跟踪过程指标以确定对ERP的依从性。患者必须接受>70%的路径要素才能被视为ERP的一部分(n = 60)。如果患者错过>30%的要素,则将他们作为传统路径进行分析(n = 52)。患者人口统计学、体重指数或糖化血红蛋白方面无显著差异。ERP组患者更可能是择期手术(76.7%对48.1%;P = .0004)以及慢性肢体威胁性缺血手术(76.7%对48.1%;P = .001),而不太可能是紧急或急诊手术。在膝下搭桥靶点频率或手术持续时间方面未观察到显著差异。ERP组对10项围手术期过程指标的依从性范围为28%至98%。术前教育(81.6%)、洗必泰清洗(80.0%)、术后活动(90.0%)、早期固体饮食(98.3%)和术后阿片类药物节省策略(98.3%)的依从性最为成功。挑战包括术前对乙酰氨基酚(28.3%)服用、碳水化合物负荷补充(33.8%)和术后蛋白质补充(28.3%)。值得注意的是,与传统路径患者相比,ERP组患者的总住院时间显著缩短(7.8天对13.6天;P = .014)、术后住院时间(6.0天对11.0天;P = .0058)以及非计划再次手术率降低(10.0%对28.9%;P = .015)。ERP组患者的非计划再入院率有降低趋势(13.3%对26.9%;P = .095)。

结论

我们的研究结果表明,针对LEAB的ERP在择期和非择期情况下都是可行的,尽管对于因紧急或急诊指征接受手术的患者,对ERP各个要素的依从性更具挑战性。接受ERP的患者对过程指标的依从性有所改善,住院时间缩短,非计划再次手术减少。我们的结果突出了ERP对LEAB及复杂血管外科患者群体的益处以及该患者群体中一些值得考虑的潜在障碍。

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