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含顺铂化疗治疗侵袭性胸腺瘤:5例报告。

Cisplatin-containing chemotherapy in the treatment of invasive thymoma: report of five cases.

作者信息

Giaccone G, Musella R, Bertetto O, Donadio M, Calciati A

出版信息

Cancer Treat Rep. 1985 Jun;69(6):695-7.

PMID:4040423
Abstract

Invasive thymomas are rare neoplasms arising from the epithelial cells of the thymus. In this paper, we report five cases of invasive thymoma treated with cisplatin either alone or combined with etoposide. Two partial responses (lasting 1 and 27+ months from the start of chemotherapy), two minor responses (lasting 1.5 and 13+ months from the start of chemotherapy), and one mixed response were observed. Further studies with cisplatin-containing regimens are warranted in the treatment of this rare tumor.

摘要

侵袭性胸腺瘤是起源于胸腺上皮细胞的罕见肿瘤。在本文中,我们报告了5例侵袭性胸腺瘤患者,这些患者接受了单独使用顺铂或顺铂联合依托泊苷的治疗。观察到2例部分缓解(化疗开始后持续1个月和27个多月)、2例轻微缓解(化疗开始后持续1.5个月和13个多月)以及1例混合缓解。含顺铂方案的进一步研究在这种罕见肿瘤的治疗中是必要的。

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引用本文的文献

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Perioperative management and postoperative outcomes of locally advanced thymic epithelial tumors: a narrative review.局部晚期胸腺上皮肿瘤的围手术期管理与术后结局:一项叙述性综述
Mediastinum. 2023 Oct 12;8:7. doi: 10.21037/med-23-24. eCollection 2024.
2
The role of induction therapy for thymic malignancies: a narrative review.诱导治疗在胸腺恶性肿瘤中的作用:一项叙述性综述。
Mediastinum. 2020 Dec 30;4:36. doi: 10.21037/med-20-20. eCollection 2020.
3
Primary chemotherapy with adriamycin, cisplatin, vincristine and cyclophosphamide in locally advanced thymomas: a single institution experience.
多柔比星、顺铂、长春新碱和环磷酰胺用于局部晚期胸腺瘤的一线化疗:单机构经验
Br J Cancer. 1999 Nov;81(5):841-5. doi: 10.1038/sj.bjc.6690773.