Giaccone G, Musella R, Bertetto O, Donadio M, Calciati A
Cancer Treat Rep. 1985 Jun;69(6):695-7.
Invasive thymomas are rare neoplasms arising from the epithelial cells of the thymus. In this paper, we report five cases of invasive thymoma treated with cisplatin either alone or combined with etoposide. Two partial responses (lasting 1 and 27+ months from the start of chemotherapy), two minor responses (lasting 1.5 and 13+ months from the start of chemotherapy), and one mixed response were observed. Further studies with cisplatin-containing regimens are warranted in the treatment of this rare tumor.
侵袭性胸腺瘤是起源于胸腺上皮细胞的罕见肿瘤。在本文中,我们报告了5例侵袭性胸腺瘤患者,这些患者接受了单独使用顺铂或顺铂联合依托泊苷的治疗。观察到2例部分缓解(化疗开始后持续1个月和27个多月)、2例轻微缓解(化疗开始后持续1.5个月和13个多月)以及1例混合缓解。含顺铂方案的进一步研究在这种罕见肿瘤的治疗中是必要的。