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本文引用的文献

1
Determinants of maternal adherence to child vaccination in jordan: A cross-sectional study.约旦儿童疫苗接种中母亲坚持性的决定因素:一项横断面研究。
Sci Rep. 2024 Oct 20;14(1):24635. doi: 10.1038/s41598-024-74183-0.
2
Parent and family characteristics associated with reported pediatric influenza vaccination in a sample of Canadian digital vaccination platform users. An exploratory, cross-sectional study in the 2018-2019 influenza season.在加拿大数字疫苗接种平台用户样本中,与报告的儿科流感疫苗接种相关的父母和家庭特征。2018-2019 流感季节的探索性、横断面研究。
Hum Vaccin Immunother. 2024 Dec 31;20(1):2378580. doi: 10.1080/21645515.2024.2378580. Epub 2024 Jul 22.
3
Socioeconomic inequalities in vaccine uptake: A global umbrella review.疫苗接种方面的社会经济不平等:全球伞式综述。
PLoS One. 2023 Dec 13;18(12):e0294688. doi: 10.1371/journal.pone.0294688. eCollection 2023.
4
Factors affecting childhood immunization: Thematic analysis of parents and healthcare workers' perceptions.影响儿童免疫接种的因素:父母和卫生保健工作者认知的主题分析。
Hum Vaccin Immunother. 2022 Nov 30;18(6):2137338. doi: 10.1080/21645515.2022.2137338. Epub 2022 Nov 3.
5
Parental Vaccine Hesitancy and Association With Childhood Diphtheria, Tetanus Toxoid, and Acellular Pertussis; Measles, Mumps, and Rubella; Rotavirus; and Combined 7-Series Vaccination.父母对接种疫苗的犹豫与儿童白喉、破伤风类毒素和无细胞百日咳、麻疹、腮腺炎和风疹、轮状病毒和联合 7 价疫苗接种的关系。
Am J Prev Med. 2022 Mar;62(3):367-376. doi: 10.1016/j.amepre.2021.08.015. Epub 2021 Dec 8.
6
Adherence to the paediatric immunisation schedule in England.英格兰儿童免疫接种计划的依从性。
Vaccine X. 2021 Nov 3;9:100125. doi: 10.1016/j.jvacx.2021.100125. eCollection 2021 Dec.
7
Association of Diphtheria-Tetanus-Acellular Pertussis Vaccine Timeliness and Number of Doses With Age-Specific Pertussis Risk in Infants and Young Children.白喉-破伤风-无细胞百日咳疫苗及时接种和接种次数与婴儿和幼儿特定年龄百日咳风险的关联。
JAMA Netw Open. 2021 Aug 2;4(8):e2119118. doi: 10.1001/jamanetworkopen.2021.19118.
8
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The Impact of Paid Maternity Leave on the Mental and Physical Health of Mothers and Children: A Review of the Literature and Policy Implications.带薪产假对母婴身心健康的影响:文献综述与政策启示。
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疫苗接种覆盖率差异与免疫延迟:利用数字免疫平台数据评估加拿大儿童12个月龄疫苗接种完成情况

Coverage disparities and delayed immunization: Assessing 12-month vaccination completion in Canadian children using data from a digital immunization platform.

作者信息

Serhan Mohamed, Nilormi Adhiba, Ntacyabukura Blaise, Atkinson Katherine, Ducharme Robin, Hawken Steven, Ramsay Tim, Ang Joyce, Wilson Kumanan

机构信息

Clinical Epidemiology Program, The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

Bruyère Health Research Institute, Bruyère Health, Ottawa, Ontario, Canada.

出版信息

Hum Vaccin Immunother. 2025 Dec;21(1):2506286. doi: 10.1080/21645515.2025.2506286. Epub 2025 May 22.

DOI:10.1080/21645515.2025.2506286
PMID:40404591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12101581/
Abstract

On-time vaccination is essential for community protection against vaccine-preventable diseases. Insufficient on-time coverage and immunization series completion can put the population at risk. This study described individual coverage and series completion rates of the 12-month dose of pneumococcal, meningococcal, and measles-mumps-rubella (MMR) vaccines, as well as predictors of these rates in Canada. We conducted a cross-sectional study with immunization data from the pan-Canadian digital vaccination tool (CANImmunize) to evaluate coverage of the 12-month dose for single and multiple-dose vaccines. We conducted bivariate and multivariate logistic regression analyses to investigate associations between factors such as account holder gender, active integration of vaccine record with a public health unit (PHU) and inclusion of linked records in CANImmunize, with vaccination coverage. We calculated crude and adjusted odds ratios and 95% confidence intervals. We analyzed 60,890 records from children aged 13 months to 18 years. Coverage of the 12-month's dose of multiple-dose vaccines was significantly lower compared to single-dose vaccines. 14.28% versus 17.23% of children who had reported the first dose of pneumococcal and meningococcal vaccines, respectively, have not received the 12-month dose of the same vaccine. Additionally, 10-13.2% of children who received the 12-month dose of pneumococcal, meningococcal, and MMR vaccines received the vaccine late (13+ months). Based on our data, there is a gap in the coverage of the 12-month dose between single and multiple-dose vaccines, and the 12-month dose was delayed for a proportion of children. Reminder interventions targeting populations with identified predictors of sub-optimal coverage may be valuable.

摘要

按时接种疫苗对于社区预防疫苗可预防疾病至关重要。按时接种覆盖率不足和免疫系列完成率不足会使人群面临风险。本研究描述了加拿大肺炎球菌、脑膜炎球菌和麻疹-腮腺炎-风疹(MMR)疫苗12月龄剂量的个体接种覆盖率和系列完成率,以及这些比率的预测因素。我们利用全加拿大数字疫苗接种工具(CANImmunize)的免疫数据进行了一项横断面研究,以评估单剂量和多剂量疫苗12月龄剂量的接种覆盖率。我们进行了双变量和多变量逻辑回归分析,以调查诸如账户持有人性别、疫苗记录与公共卫生单位(PHU)的有效整合以及CANImmunize中链接记录的纳入等因素与疫苗接种覆盖率之间的关联。我们计算了粗比值比和调整后的比值比以及95%置信区间。我们分析了60890份13个月至18岁儿童的记录。多剂量疫苗12月龄剂量的接种覆盖率明显低于单剂量疫苗。分别报告了第一剂肺炎球菌和脑膜炎球菌疫苗的儿童中,有14.28%和17.23%未接种同一种疫苗的12月龄剂量。此外,接种肺炎球菌、脑膜炎球菌和MMR疫苗12月龄剂量的儿童中有10%-13.2%接种疫苗较晚(13个月以上)。根据我们的数据,单剂量和多剂量疫苗在12月龄剂量的接种覆盖率上存在差距,并且一部分儿童的12月龄剂量接种被推迟。针对具有次优覆盖率预测因素人群的提醒干预措施可能很有价值。