Monet-Kuntz C, Terqui M
Int J Androl. 1985 Apr;8(2):129-38. doi: 10.1111/j.1365-2605.1985.tb00826.x.
The effects of an endogenous LH pulse on the testicular concentration of testosterone, cytoplasmic androgen receptor content and androgen binding protein (ABP) content was studied in rams. Blood was collected from 36 rams for at least 14 h and their testes then removed. Animals were then grouped according to the interval from their last LH pulse and the time of slaughter. The concentration of testosterone in the testis was highest during the first h following the LH pulse and returned to its baseline within 5 h. There was a 60% reduction in the testicular content of cytoplasmic androgen receptors at 3 h after the LH pulse, followed by slow replenishment. The testicular content of ABP was highest at 4 h after the LH pulse. It is in the testis concluded that the pulsatility of LH and testosterone induces a pulsatile translocation of cytoplasmic androgen receptors.
研究了内源性促黄体生成素（LH）脉冲对公羊睾丸中睾酮浓度、细胞质雄激素受体含量和雄激素结合蛋白（ABP）含量的影响。从36只公羊采集血液至少14小时，然后摘除其睾丸。随后根据距其最后一次LH脉冲的间隔时间和屠宰时间将动物分组。睾丸中睾酮浓度在LH脉冲后的第1小时内最高，并在5小时内恢复到基线水平。LH脉冲后3小时，细胞质雄激素受体的睾丸含量降低了60%，随后缓慢补充。ABP的睾丸含量在LH脉冲后4小时最高。由此得出结论，LH和睾酮的脉冲性诱导了细胞质雄激素受体的脉冲性易位。
