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[肥厚型心肌病不同形态学变异的临床-器械比较特征]

[Comparative clinico-instrumental characteristics of different morphological variants of hypertrophic cardiomyopathy].

作者信息

Popov V G, Sedov V P, Gruzdev A K, Alushkov M V

出版信息

Kardiologiia. 1985 May;25(5):14-9.

PMID:4040586
Abstract

Six morphologic variants of hypertrophic cardiomyopathy (HCMP) have been identified on the basis of the echocardiographically-documented extent and localization of left-ventricular hypertrophy in 34 patients with HCMP. More than half of the patients had no complaints. The more characteristic echocardiographic features of the disease included a considerable thickening of one or more departments within the left ventricle, the size of its cavity being diminished. In most cases, HCMP was associated with considerably enlarged R waves on the electrocardiograms from 35 precordial leads that were usually combined with ST segment depression and T wave inversion. The latter two features often provided grounds for a hyperdiagnosis of coronary heart disease (CHD). What distinguishes HCMP from CHD is the discrepancy between marked and persistent pathologic electrocardiographic changes and a relatively uneventful clinical picture of the disease. The comparison of echocardiographic and ECG charting data allows a more detailed assessment of the kind of left-ventricular hypertrophy in HCMP patients, and can be used in the differential diagnosis of HCMP vs. CHD.

摘要

根据超声心动图记录的34例肥厚型心肌病(HCMP)患者左心室肥厚的程度和部位,已确定了HCMP的六种形态学变异型。超过半数的患者无主诉症状。该疾病更具特征性的超声心动图表现包括左心室内一个或多个部位显著增厚,其腔室大小减小。在大多数情况下,HCMP与来自35个心前区导联心电图上的R波明显增大有关,且通常伴有ST段压低和T波倒置。后两个特征常常成为冠心病(CHD)过度诊断的依据。HCMP与CHD的区别在于显著且持续的病理性心电图改变与相对平稳的疾病临床表现之间存在差异。超声心动图和心电图检查数据的比较有助于更详细地评估HCMP患者左心室肥厚的类型,并可用于HCMP与CHD的鉴别诊断。

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