Smith Jillian A, Sylvester Scott, Norez Daniel, Kelly William D, Touze Hugues, Crawford Kristina M, Celso Brian G, Murray John D
Department of Surgery/Division of Plastic Surgery, University of Florida College of Medicine at Jacksonville, Jacksonville, FL, USA.
School of Medicine/Division of Rheumatology, University of Colorado at Colorado, Denver, CO, USA.
Gland Surg. 2025 Apr 30;14(4):611-617. doi: 10.21037/gs-2024-532. Epub 2025 Apr 25.
Fluorescent intraoperative tissue angiography (FITA) provides real-time perfusion analysis that predicts which tissues will progress to postoperative ischemic necrosis. This technology helps guide the surgeon to resect the at-risk tissues preemptively. The purpose of our study was to evaluate whether clinical outcomes are affected by the level of experience with FITA for superomedial-pedicle breast reduction (SBR).
A retrospective, sequential series of 50 patients who underwent single-surgeon bilateral reduction mammaplasty using FITA (SPY Elite, Stryker, Kalamazoo, MI, USA) between April 2015 and September 2020 were included in the study. Two groups from the series were formed: the first three years with 25 patients (Group A) and the last three years with 25 patients (Group B). Operative data included FITA perfusion indices (medial breast, lateral breast, and nipple-areolar complex) and resection weight. Post-operative complications such as return to operating room (RTOR), and skin or nipple loss were reported.
Two statistically significant changes were observed: superomedial perfusion indices increased (right breast P<0.001, left breast P=0.02) and resection weights decreased (right breast P=0.044, left breast P=0.007). While the number of observed complications (nipple sensation, minor skin loss, RTOR), decreased in Group B compared to Group A, the difference was not statistically significant (P=0.62). The rate of minor skin or nipple loss was reduced by 57% in Group B versus Group A).
FITA may help guide the preservation of perforators in the breast reduction pedicle. Though doing so did not reveal any statistical reduction in the number of complications in our study. These findings require further investigation for definitive conclusions.
术中荧光组织血管造影术(FITA)可提供实时灌注分析,预测哪些组织会进展为术后缺血性坏死。这项技术有助于指导外科医生提前切除有风险的组织。我们研究的目的是评估临床结果是否受上内侧蒂乳房缩小术(SBR)中FITA经验水平的影响。
回顾性、连续性纳入2015年4月至2020年9月期间由单一外科医生使用FITA(美国密歇根州卡拉马祖市史赛克公司的SPY Elite)进行双侧乳房缩小术的50例患者。该系列患者分为两组:前三年的25例患者(A组)和后三年的25例患者(B组)。手术数据包括FITA灌注指数(乳房内侧、乳房外侧和乳头乳晕复合体)和切除重量。报告术后并发症,如返回手术室(RTOR)、皮肤或乳头丢失情况。
观察到两个具有统计学意义的变化:上内侧灌注指数增加(右乳P<0.001,左乳P=0.02),切除重量减少(右乳P=0.044,左乳P=0.007)。虽然B组观察到的并发症数量(乳头感觉、轻微皮肤丢失、RTOR)与A组相比有所减少,但差异无统计学意义(P=0.62)。B组与A组相比,轻微皮肤或乳头丢失率降低了57%。
FITA可能有助于指导在乳房缩小术蒂部保留穿支血管。尽管如此,在我们的研究中这样做并未显示并发症数量有任何统计学上的减少。这些发现需要进一步研究以得出明确结论。