Cao Qianqian, Cheng Cheng, Dai Zhipeng
Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Zhengzhou, Henan, China.
Front Oncol. 2025 May 8;15:1597194. doi: 10.3389/fonc.2025.1597194. eCollection 2025.
Phosphaturic mesenchymal tumor (PMT) is a rare tumor disease that often leads to tumor-induced osteomalacia (TIO). The typical manifestations of this disease include hypophosphatemia and osteomalacia. The main symptom in most PMT patients is diffuse pain throughout the body. However, we report a PMT patient with typical histological features but without hypophosphatemia and TIO. This patient only presented with pain in the right knee joint. At 6 months and 1 year after surgery, follow-up revealed that the patient's swelling and pain in the right knee joint had disappeared. Moreover, the imaging and biochemical examinations conducted at the local hospital showed normal results.
磷酸尿性间叶肿瘤(PMT)是一种罕见的肿瘤疾病,常导致肿瘤诱导的骨软化症(TIO)。该疾病的典型表现包括低磷血症和骨软化症。大多数PMT患者的主要症状是全身弥漫性疼痛。然而,我们报告了一名具有典型组织学特征但无低磷血症和TIO的PMT患者。该患者仅表现为右膝关节疼痛。术后6个月和1年的随访显示,患者右膝关节的肿胀和疼痛已消失。此外,当地医院进行的影像学和生化检查结果均正常。