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先天性巨结肠症的再次拖出术——基于拖出术类型的结局荟萃分析

Redo Pull-through in Hirschsprungs Disease - A Meta-Analysis of Outcomes Based on type of Pull-through.

作者信息

Rao M Srinivasa, Prasad D Kalyan Ravi, Reddy J Bhaskar

机构信息

Department of Surgery, Maharajah Institute of Medical Sciences Hospital, Vizianagaram, Andhra Pradesh, India.

Department of Paediatric Surgery, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India.

出版信息

J Indian Assoc Pediatr Surg. 2025 May-Jun;30(3):330-342. doi: 10.4103/jiaps.jiaps_279_24. Epub 2025 Apr 15.

Abstract

PURPOSE

The meta-analysis investigates the effects of redo pull-through (PT) surgeries on bowel function outcomes in patients with rectosigmoid and long-segment Hirschsprung's disease (HD) who have already undergone an initial PT. By comparing different redo PT techniques, this study explores whether specific approaches yield better postoperative bowel function.

METHODOLOGY

A literature search was conducted for articles on redo PT for HD; this included PubMed and ScienceDirect databases. The search terms or MeSH words "Hirschsprung disease" OR "congenital megacolon" AND "re-do pull through" OR "re-do" OR "reoperation," connected by two Boolean operators "OR" and "AND," were used to search the databases for relevant articles.

RESULTS

Fifteen articles of interest comprising 374 patients receiving redo PT were selected for analysis. The results suggest that selecting a redo PT method tailored to the patient's unique anatomical and surgical history may substantially improve functional outcomes, highlighting the potential for individualized strategies to enhance recovery and long-term quality of life for those requiring reoperation.

CONCLUSION

The findings indicate that the Swenson redo PT approach yielded better bowel function outcomes compared to other techniques. While redo PT procedures were effective in reducing fecal incontinence, the incidence of enterocolitis remained consistent across the various approaches.

摘要

目的

本荟萃分析旨在研究再次拖出式(PT)手术对已接受初次PT手术的直肠乙状结肠型和长段型先天性巨结肠(HD)患者肠道功能结局的影响。通过比较不同的再次PT技术,本研究探讨特定方法是否能产生更好的术后肠道功能。

方法

对关于HD再次PT的文章进行文献检索;检索数据库包括PubMed和ScienceDirect。检索词或医学主题词“先天性巨结肠”或“先天性巨结肠症”以及“再次拖出术”或“再次手术”或“再次操作”,通过两个布尔运算符“或”和“与”连接,用于在数据库中搜索相关文章。

结果

选取15篇涉及374例接受再次PT患者的相关文章进行分析。结果表明,根据患者独特的解剖结构和手术史选择合适的再次PT方法可能显著改善功能结局,这凸显了个体化策略对提高再次手术患者恢复情况和长期生活质量的潜力。

结论

研究结果表明,与其他技术相比,斯文森再次PT方法产生了更好的肠道功能结局。虽然再次PT手术在减少大便失禁方面有效,但各种方法的小肠结肠炎发病率保持一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3162/12094608/bce77b555c8e/JIAPS-30-330-g001.jpg

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