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母体肥胖、妊娠期糖尿病与巨大胎儿:偶然关系还是机制性关联?

Maternal Obesity, Gestational Diabetes, and Fetal Macrosomia: An Incidental or a Mechanistic Relationship?

作者信息

Salameh Mohammad A, Oniya Olubunmi, Chamseddine Reem S, Konje Justin C

机构信息

Department of Medical Education, Weill Cornell Medicine - Qatar, Doha, Qatar.

Department of Obstetrics & Gynecology, Sidra Medicine, Doha, Qatar.

出版信息

Matern Fetal Med. 2021 Oct 4;5(1):27-30. doi: 10.1097/FM9.0000000000000125. eCollection 2023 Jan.

Abstract

Gestational diabetes mellitus (GDM) is a well-established risk factor for fetal macrosomia. A significant number of patients with GDM also suffer from obesity, a factor associated with fetal macrosomia. An important question is whether GDM is independently associated with fetal macrosomia, or whether this relationship is merely the result of maternal obesity acting as a confounder. In this review of the literature, we attempt to further elucidate the relationship between GDM, maternal obesity, and fetal macrosomia.

摘要

妊娠期糖尿病(GDM)是公认的胎儿巨大儿的危险因素。大量GDM患者也患有肥胖症,而肥胖是与胎儿巨大儿相关的一个因素。一个重要的问题是,GDM是否与胎儿巨大儿独立相关,或者这种关系仅仅是作为混杂因素的母体肥胖的结果。在这篇文献综述中,我们试图进一步阐明GDM、母体肥胖和胎儿巨大儿之间的关系。

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本文引用的文献

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Factors associated with fetal macrosomia.与胎儿巨大儿相关的因素。
Rev Saude Publica. 2019 Dec 2;53:100. doi: 10.11606/s1518-8787.2019053001269. eCollection 2019.
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Gestational diabetes mellitus in association with macrosomia in Iran: a meta-analysis.伊朗妊娠期糖尿病与巨大儿的关联:一项荟萃分析。
J Diabetes Metab Disord. 2019 Feb 21;18(1):41-50. doi: 10.1007/s40200-019-00388-0. eCollection 2019 Jun.

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