Baranwal Anshika, Gadhvi Mahesh Arjundan, Agrawal Mohit, Srivastav Shival, Dixit Abhinav
Physiology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, IND.
Neurosurgery, All India Institute of Medical Sciences, Jodhpur, Jodhpur, IND.
Cureus. 2025 Apr 22;17(4):e82794. doi: 10.7759/cureus.82794. eCollection 2025 Apr.
Facial nerve compression by blood vessels near the brainstem can cause hemifacial spasm (HFS). There are two treatment options for this condition: botulinum toxin and surgical microvascular decompression (MVD). During microvascular decompression, the facial nerve is separated from the offending vessel, and intraoperative neuromonitoring in these patients demonstrates abnormal muscle response (AMR), which is known as the lateral spread response (LSR). Though the disappearance of lateral spread response is a hallmark of successful microvascular decompression, little information is available about its physiological origin and diagnostic utility. In the present review, we have attempted to address the aforementioned caveats about lateral spread response with an emphasis on the intraoperative utility and diagnostic role of this electrophysiological phenomenon.
脑干附近血管对面神经的压迫可导致面肌痉挛（HFS）。针对这种情况有两种治疗选择：肉毒杆菌毒素和外科微血管减压术（MVD）。在微血管减压术中，面神经与致病血管分离，这些患者的术中神经监测显示出异常肌肉反应（AMR），即所谓的侧方扩散反应（LSR）。尽管侧方扩散反应的消失是微血管减压术成功的标志，但关于其生理起源和诊断效用的信息却很少。在本综述中，我们试图解决上述关于侧方扩散反应的问题，重点关注这种电生理现象的术中效用和诊断作用。
