Pan Weichun, Wen Ya, Liao Huabin, Gu Feina, Yang Yuexi, Zhou Jianzhong, Zhang Qiuping, Niu Fuge
Food Safety Key Lab of Zhejiang Province, School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, China.
School of Food Science and Pharmacy, Xinjiang Agricultural University, Urumchi, China.
J Sci Food Agric. 2025 Sep;105(12):6827-6838. doi: 10.1002/jsfa.14395. Epub 2025 May 23.
Docosahexaenoic acid (DHA) is an essential nutrient for infant growth. However, DHA molecules are rich in unsaturated double bonds, making them highly sensitive to oxygen, light and heat, causing fish oil to oxidize easily, as well as leading to a loss of its physiological function and nutritional value.
The present study aimed to increase the oxidative stability of DHA. Fish oil emulsion was prepared using ovalbumin (OVA)/sodium carboxymethylcellulose (CMC)-curcumin (Cur) colloidal particles. The results showed that a ternary colloidal particles emulsion transport system was constructed and that the OVA/CMC colloidal particles loaded with curcumin were successfully adsorbed to the oil-water interface, forming a film with oxidation defense and interface barrier properties. The emulsion stabilized by ternary colloidal particles had strong storage and oxidation stability. Especially when the OVA/CMC ratio was 2:1, the oxidation stability and storage stability of DHA in fish oil emulsion were improved, respectively.
The oxidative stability and storage stability of DHA in fish oil emulsions were enhanced synergistically by OVA/CMC-Cur ternary colloidal particles. This finding provides a theoretical framework for expanding the application of OVA/CMC-Cur particles in nutrient delivery. © 2025 Society of Chemical Industry.
二十二碳六烯酸(DHA)是婴儿生长必需的营养素。然而,DHA分子富含不饱和双键,使其对氧气、光和热高度敏感,导致鱼油容易氧化,进而使其生理功能和营养价值丧失。
本研究旨在提高DHA的氧化稳定性。使用卵清蛋白(OVA)/羧甲基纤维素钠(CMC)-姜黄素(Cur)胶体颗粒制备鱼油乳液。结果表明,构建了三元胶体颗粒乳液输送系统,负载姜黄素的OVA/CMC胶体颗粒成功吸附到油水界面,形成具有抗氧化防御和界面屏障性能的膜。由三元胶体颗粒稳定的乳液具有很强的储存和氧化稳定性。特别是当OVA/CMC比例为2:1时,鱼油乳液中DHA的氧化稳定性和储存稳定性分别得到提高。
OVA/CMC-Cur三元胶体颗粒协同增强了鱼油乳液中DHA的氧化稳定性和储存稳定性。这一发现为扩大OVA/CMC-Cur颗粒在营养递送中的应用提供了理论框架。©2025化学工业协会。