Martí Lorena, Garriga-Cazorla Helena, Roman-Juan Josep, Miró Jordi
Unit for the Study and Treatment of Pain - ALGOS, Universitat Rovira i Virgili, Catalonia, Spain.
Department of Psychology, Research Center for Behaviour Assessment (CRAMC), Catalonia, Spain.
Eur J Pain. 2025 Jul;29(6):e70038. doi: 10.1002/ejp.70038.
The aim of this systematic review is to synthesise the findings about the role of family-related factors in chronic pain in children and adolescents.
We conducted a search of the following electronic databases: PubMed/MedLine, CINHAL, PsychINFO, PubPsych, Scopus and Web of Science from inception to July 2024. We only included studies involving children and adolescents (up to 19 years old) with chronic pain and studies that involved the parents or families of these children.
A total of 24,049 articles were retrieved, of which 20,921 were screened for evaluation and 119 were included in the review.
Most of the studies were cross-sectional with a moderate or high risk of bias, reporting on the parenting individual-, dyadic-, and contextual-related factors. In the included studies, significant associations emerged between a number of family-related factors and chronic pain and related disability in 16 of the 119 studies that had been judged to be of good methodological quality.
The data from these studies showed significant associations between parental individual variables (e.g., parent's mental health), dyadic variables (e.g., parental responses towards their children's pain), and context-related variables (e.g., family functioning), and some key pain-related outcomes, including pain chronification, pain intensity, pain frequency, pain extent, pain-related interference, the ability to cope with chronic pain, and pain-related disability in children and adolescents. Therefore, these factors may be important targets for the prevention and management of chronic pain in children and adolescents.
本系统评价的目的是综合有关家庭相关因素在儿童和青少年慢性疼痛中作用的研究结果。
我们检索了以下电子数据库：自数据库创建至2024年7月的PubMed/MedLine、CINHAL、PsychINFO、PubPsych、Scopus和Web of Science。我们仅纳入涉及患有慢性疼痛的儿童和青少年（19岁及以下）的研究，以及涉及这些儿童的父母或家庭的研究。
共检索到24049篇文章，其中20921篇经筛选进行评估，119篇纳入本综述。
大多数研究为横断面研究，存在中度或高度偏倚风险，报告了与养育子女个体、二元关系和情境相关的因素。在纳入的研究中，在119项被判定为方法学质量良好的研究中，有16项发现一些家庭相关因素与慢性疼痛及相关残疾之间存在显著关联。
这些研究的数据显示，父母个体变量（如父母的心理健康）、二元关系变量（如父母对子女疼痛的反应）和情境相关变量（如家庭功能）与一些关键的疼痛相关结果之间存在显著关联，这些结果包括疼痛慢性化、疼痛强度、疼痛频率、疼痛范围、疼痛相关干扰、应对慢性疼痛的能力以及儿童和青少年的疼痛相关残疾。因此，这些因素可能是预防和管理儿童和青少年慢性疼痛的重要目标。
