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增强烧伤恢复:关于电刺激在加速愈合方面益处的系统评价

Enhancing Burn Recovery: A Systematic Review on the Benefits of Electrical Stimulation in Accelerating Healing.

作者信息

Edwick Dale O, Burns Kerry L, Buonvecchi Lara N, Wang Xiaolu, Lim Audrey M, Edgar Dale W

机构信息

School of Allied Health, Faculty of Health Science, Curtin University, Bentley, WA 6102, Australia.

State Adult Burn Unit, Level 4, Fiona Stanley Hospital, Murdoch, WA 6150, Australia.

出版信息

Eur Burn J. 2025 May 5;6(2):21. doi: 10.3390/ebj6020021.

Abstract

Prolonged healing time of acute burn wounds is associated with increased pain, infection, risk of scarring, poorer mobility and higher financial and emotional burden. Electrical stimulation (ES) reduces healing time in chronic wounds; however, its reported use on acute burn wounds is limited. This systematic review (SR) aimed to evaluate the relative benefit of ES compared to routine wound care on the healing time of acute burn wounds in adults. The online databases queried included Cochrane Database of SR's, MEDLINE, EMBASE, PUBMED and CINAHL. The search criteria included RCTs involving the application of ES of varying voltage, duration and modality in acute burn patients aged ≥18 years. The primary outcome investigated was days to burn wound closure, while the secondary outcomes included edema and infection. Four RCTs were discovered, involving a total of 143 participants with a mean age 35.5 years. Two RCTs demonstrated (a) 36% (2.6 days) reduction in time to wound closure with ES ( < 0.001); and (b) significant reduction in wound area with ES (11.2 ± 3.2 cm, < 0.001) compared to controls at 21 days. Two RCTs found ES promoted better wound-healing environments, reducing edema, bacterial infection, and biofilm. This review highlighted low-risk wound-healing benefits with ES as a feasible adjunct to routine burn care.

摘要

急性烧伤创面愈合时间延长与疼痛加剧、感染、瘢痕形成风险增加、活动能力下降以及更高的经济和情感负担相关。电刺激(ES)可缩短慢性伤口的愈合时间;然而,其在急性烧伤创面上的应用报道有限。本系统评价(SR)旨在评估与常规伤口护理相比,ES对成人急性烧伤创面愈合时间的相对益处。查询的在线数据库包括Cochrane系统评价数据库、MEDLINE、EMBASE、PUBMED和CINAHL。搜索标准包括涉及对年龄≥18岁的急性烧伤患者应用不同电压、持续时间和方式的ES的随机对照试验(RCT)。研究的主要结局是烧伤创面闭合天数,次要结局包括水肿和感染。共发现4项RCT,涉及143名参与者,平均年龄35.5岁。两项RCT表明:(a)与对照组相比,ES使伤口闭合时间缩短36%(2.6天)(<0.001);(b)在21天时,与对照组相比,ES使伤口面积显著减小(11.2±3.2平方厘米,<0.001)。两项RCT发现ES可促进更好的伤口愈合环境,减轻水肿、细菌感染和生物膜。本评价强调ES作为常规烧伤护理的可行辅助手段,具有低风险的伤口愈合益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4503/12101274/0fde2cdd6f82/ebj-06-00021-g001.jpg

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