Black N
Int J Pediatr Otorhinolaryngol. 1985 Jul;9(2):121-33. doi: 10.1016/s0165-5876(85)80012-4.
A case-control study was carried out to investigate many of the proposed causes of glue ear in childhood. One hundred and fifty cases with two matched controls were found to be remarkably similar in nearly all medical and social aspects of their past and present lives, thus providing no support for many of the currently held views on the aetiology of glue ear. Of the 5 factors which were found to increase the risk of a child undergoing surgery for glue ear, only one of these is thought to be related to the development of the condition, rather than to the chances of its detection. This factor was parental smoking (RR 1.64). The 4 other risk factors appear to influence the chance of glue ear being detected, diagnosed and referred for surgical treatment - the child's mother being employed outside the home, but only if the father is employed in non-manual work (RR 3.0); attending pre-school day-care (RR 2.00); having an older sibling who had been diagnosed as suffering from glue ear (RR 1.84); and having been born locally (in Oxfordshire) (RR 1.89). Possible explanations for these social and behavioural factors are discussed.
开展了一项病例对照研究，以调查儿童分泌性中耳炎诸多可能的病因。研究发现，150例病例及其配对的对照组在过去和现在生活的几乎所有医学和社会方面都极为相似，因此目前关于分泌性中耳炎病因的许多观点都缺乏依据。在发现的5个会增加儿童因分泌性中耳炎接受手术风险的因素中，只有一个被认为与该病症的发展有关，而非与病症被发现的几率有关。这个因素是父母吸烟（相对危险度为1.64）。其他4个风险因素似乎会影响分泌性中耳炎被发现、诊断并转介接受手术治疗的几率——孩子的母亲在外工作，但前提是父亲从事非体力工作（相对危险度为3.0）；孩子参加学前日托（相对危险度为2.00）；有一个被诊断患有分泌性中耳炎的哥哥或姐姐（相对危险度为1.84）；以及在当地（牛津郡）出生（相对危险度为1.89）。文中讨论了这些社会和行为因素的可能解释。
