Caxeiro Giovanna Luiza, Ribeiro Davi Knoll, Romero Rafael Dias, Rosano Marcello, Oliveira Santos Rodrigo, Catafesta Neves Murilo, Abrahao Marcio
Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
Braz J Otorhinolaryngol. 2025 Jul;91 Suppl 1(Suppl 1):101606. doi: 10.1016/j.bjorl.2025.101606. Epub 2025 May 22.
The aim of this study was to analyze the peculiarities of the collection sites.
It is a prospective study of patients undergoing parathyroidectomy by HPTP, with PTH values in the peripheral collection and from the ipsilateral VJI at times: initial (T0) and 10-min after removal of the diseased gland (T10).
61 participants were evaluated. The median PTH at baseline was 147.9 in the peripheral vein and 476.58 in the central vein. The median at T10 was 36 in the peripheral vein and 33 in the central vein. The central vein values showed a greater reduction, with the peripheral values showing a median decay of 74.35%, while the central values dropped by 82.38%. In the initial collection, PTH values were higher in the central vein, while they tended towards homeostasis after the removal of the diseased gland, regardless of the collection site. Thus, the average decay values from the central vein collections were higher and more significant than those from the peripheral veins.
The use of central values thus implies greater reliability for to intraoperative monitoring, with long-term comparative studies still being necessary to determine more targeted and effective surgical approaches.
Level III.
本研究旨在分析采集部位的特点。
这是一项对接受高分辨率甲状旁腺手术（HPTP）的患者进行的前瞻性研究，在初始（T0）和切除病变腺体后10分钟（T10）时，对外周采集和同侧颈内静脉（VJI）采集的甲状旁腺激素（PTH）值进行检测。
对61名参与者进行了评估。基线时外周静脉的PTH中位数为147.9，中心静脉为476.58。T10时外周静脉的中位数为36，中心静脉为33。中心静脉的值下降幅度更大，外周值的中位数下降了74.35%，而中心值下降了82.38%。在初始采集中，中心静脉的PTH值较高，而在切除病变腺体后，无论采集部位如何，PTH值都趋于稳态。因此，中心静脉采集的平均下降值高于外周静脉，且更显著。
因此，使用中心值意味着术中监测具有更高的可靠性，但仍需要长期的比较研究来确定更有针对性和有效的手术方法。
三级。
