Takahashi Haruka, Okada Yohei, Hong Dehan, Quah Dennis, Leong Benjamin Sh, Ng Yih Yng, Shahidah Nur, Goh Geraldine Sy, Yazid Muhammad, Suzuki Kensuke, Neumar Robert W, Ong Marcus Eng Hock
Pre-hospital and Emergency Research Centre, Health Services and Systems Research, Duke-NUS Medical School, Singapore; The Graduate School of Medical and Health Science, Nippon Sport Science University, Japan.
Pre-hospital and Emergency Research Centre, Health Services and Systems Research, Duke-NUS Medical School, Singapore; Department of Preventive Services, Graduate School of Medicine, Kyoto University, Japan.
Resuscitation. 2025 Aug;213:110651. doi: 10.1016/j.resuscitation.2025.110651. Epub 2025 May 21.
We aimed to investigate the association between the time taken to start dispatcher-assisted cardiopulmonary resuscitation (DA-CPR) and survival outcomes for OHCA.
This was a retrospective analysis using the Singapore Pan-Asian Resuscitation Outcomes Study data between 2012 and 2021. We included all adult, witnessed, non-traumatic OHCA patients who received DA-CPR. The exposure of interest was time interval from emergency call to start of DA-CPR. Patients were divided into three groups based on previous studies. The outcome was defined as survival to 30-days with favorable neurological outcomes. Multivariable logistic regression analysis was performed. Restricted cubic spline curves were used to explore non-linear relationships.
3,861 OHCA patients were included in this analysis. Patients were grouped as follows: short (0-179 s), medium (180-239 s), and long (≥240 s) to start DA-CPR. Adjusted odds ratios [95% CI] for survival to 30-days with favorable neurological outcomes were: medium 0.82 [0.52-1.28], long 0.63 [0.40-0.98]. The restricted cubic spline curve showed a monotonic decrease in the odds ratio for survival to 30-days with favorable neurological outcomes.
This study found that among non-traumatic, witnessed OHCA patients who received DA-CPR, a shorter time to start DA-CPR was associated with better 30-day survival with favorable neurological outcomes.
我们旨在研究调度员辅助心肺复苏（DA-CPR）开始时间与院外心脏骤停（OHCA）患者生存结局之间的关联。
这是一项回顾性分析，使用了2012年至2021年新加坡泛亚复苏结局研究的数据。我们纳入了所有接受DA-CPR的成年、有目击者、非创伤性OHCA患者。感兴趣的暴露因素是从紧急呼叫到开始DA-CPR的时间间隔。根据先前的研究，将患者分为三组。结局定义为存活至30天且神经功能结局良好。进行了多变量逻辑回归分析。使用受限立方样条曲线来探索非线性关系。
本分析纳入了3861例OHCA患者。患者按以下方式分组：开始DA-CPR的时间短（0-179秒）、中（180-239秒）和长（≥240秒）。存活至30天且神经功能结局良好的调整优势比[95%置信区间]为：中0.82[0.52-1.28]，长0.63[0.40-0.98]。受限立方样条曲线显示，存活至30天且神经功能结局良好的优势比呈单调下降。
本研究发现，在接受DA-CPR的非创伤性、有目击者的OHCA患者中，开始DA-CPR的时间越短，30天存活且神经功能结局良好的可能性越大。
