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少即是多?生物可吸收血管支架与药物洗脱金属支架:10年随访

Less Is More?: Bioresorbable Vascular Scaffold vs Drug-Eluting Metallic Stent: 10-Year Follow-Up.

作者信息

Lai Chin-Wai, Chung Tak-Shun

机构信息

Division of Cardiology, Department of Medicine and Geriatrics, United Christian Hospital, Kwun Tong, Hong Kong.

Division of Cardiology, Department of Medicine and Geriatrics, United Christian Hospital, Kwun Tong, Hong Kong.

出版信息

JACC Case Rep. 2025 May 21;30(11):103315. doi: 10.1016/j.jaccas.2025.103315. Epub 2025 Apr 9.

DOI:10.1016/j.jaccas.2025.103315
PMID:40409853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12243037/
Abstract

BACKGROUND

ABSORB bioresorbable vascular scaffold (BVS) emerged in 2012 aiming to provide early mechanical support while restoring normal vascular function after its complete resorption. Subsequent trials raised safety concerns over early higher scaffold thrombosis rates compared with metallic drug-eluting stent (DES). However, very long-term outcomes of BVS remain insufficiently reported.

CASE SUMMARY

A 71-year-old man presenting with stable angina had both BVS and DES implanted in the same vessel in 2014. Restudy angiogram and intravascular optical coherence tomography showed satisfactory outcome of both stents 10 years later.

DISCUSSION

This case illustrated patient and lesion selection, proper sizing, predilatation, and postdilatation contributed to successful long-term outcome of BVS.

TAKE-HOME MESSAGES: This case demonstrated satisfactory 10-year outcome of BVS that is comparable with DES in the same vessel of the same patient. The patient and lesion selection, proper sizing, predilatation, and postdilatation implantation techniques are the keys to satisfactory long-term outcome of BVS.

摘要

背景

ABSORB生物可吸收血管支架(BVS)于2012年问世,旨在在完全吸收后恢复正常血管功能的同时提供早期机械支撑。随后的试验引发了对其早期支架血栓形成率高于金属药物洗脱支架(DES)的安全性担忧。然而,BVS的极长期结果报道仍不充分。

病例摘要

一名71岁男性,因稳定型心绞痛于2014年在同一血管内植入了BVS和DES。10年后复查血管造影和血管内光学相干断层扫描显示两个支架的结果均令人满意。

讨论

该病例表明,患者和病变的选择、合适的尺寸、预扩张和后扩张有助于BVS获得成功的长期结果。

要点

该病例显示BVS在同一患者的同一血管中10年的结果令人满意,与DES相当。患者和病变的选择、合适的尺寸、预扩张和后扩张植入技术是BVS获得满意长期结果的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb68/12243037/9354e0b4c355/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb68/12243037/717bedfeca07/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb68/12243037/f9ef68b15a75/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb68/12243037/e5d11ad8342f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb68/12243037/9354e0b4c355/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb68/12243037/717bedfeca07/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb68/12243037/f9ef68b15a75/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb68/12243037/e5d11ad8342f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb68/12243037/9354e0b4c355/gr3.jpg

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本文引用的文献

1
Time-Varying Outcomes With the Absorb Bioresorbable Vascular Scaffold During 5-Year Follow-up: A Systematic Meta-analysis and Individual Patient Data Pooled Study.5 年随访期间 Absorb 生物可吸收血管支架的时变结果:系统评价和个体患者数据合并研究。
JAMA Cardiol. 2019 Dec 1;4(12):1261-1269. doi: 10.1001/jamacardio.2019.4101.
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Comparison of an everolimus-eluting bioresorbable scaffold with an everolimus-eluting metallic stent in routine PCI: three-year clinical outcomes from the AIDA trial.依维莫司洗脱生物可吸收支架与依维莫司洗脱金属支架在常规经皮冠状动脉介入治疗中的比较:AIDA试验的三年临床结果
EuroIntervention. 2019 Sep 20;15(7):603-606. doi: 10.4244/EIJ-D-19-00325.
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Effect of Technique on Outcomes Following Bioresorbable Vascular Scaffold Implantation: Analysis From the ABSORB Trials.
生物可吸收血管支架置入术后技术对结局的影响:ABSORB 试验分析。
J Am Coll Cardiol. 2017 Dec 12;70(23):2863-2874. doi: 10.1016/j.jacc.2017.09.1106. Epub 2017 Oct 31.
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First Observation of a "Golden Tube" After Complete Resorption of a Bioresorbable Vascular Scaffold in a Transplanted Patient With Cardiac Allograft Vasculopathy.
JACC Cardiovasc Interv. 2017 Jun 26;10(12):1270-1272. doi: 10.1016/j.jcin.2017.03.040. Epub 2017 May 31.
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Bioresorbable Scaffolds versus Metallic Stents in Routine PCI.生物可吸收支架与金属支架在常规 PCI 中的应用比较。
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Comparison of an everolimus-eluting bioresorbable scaffold with an everolimus-eluting metallic stent for the treatment of coronary artery stenosis (ABSORB II): a 3 year, randomised, controlled, single-blind, multicentre clinical trial.对比依维莫司洗脱生物可吸收支架与依维莫司洗脱金属支架治疗冠状动脉狭窄的疗效(ABSORB II):3 年随机、对照、单盲、多中心临床试验。
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