Palmas C, Conchedda M, Bortoletti G, Gabriele F
Boll Ist Sieroter Milan. 1985;64(3):216-21.
The possibility of using cell mediated immune response as a diagnostic tool has been investigated with T. spiralis laboratory/model. The feasibility of a in vitro microculture method to measure blast cell activity of lymphoblasts in mice experimentally infected with T. spiralis muscle larvae or immunized with soluble crude antigen and the lymphoproliferative response in immunized rabbits was demonstrated. The obtained results suggest that the cell mediated immune response from blood lymphocytes may be very useful to diagnose early parasite infections.
利用细胞介导的免疫反应作为诊断工具的可能性已通过旋毛虫实验室/模型进行了研究。已证明一种体外微量培养方法可用于测量实验感染旋毛虫肌幼虫或用可溶性粗抗原免疫的小鼠中淋巴细胞的母细胞活性以及免疫兔中的淋巴细胞增殖反应。所得结果表明，血液淋巴细胞介导的细胞免疫反应可能对早期寄生虫感染的诊断非常有用。
