Fernández-Carnero Samuel, Martínez-Pozas Oliver, Pecos-Martín Daniel, Pardo-Gómez Armando, Cuenca-Zaldívar Juan Nicolás, Sánchez-Romero Eleuterio A
Departamento de Fisioterapia, Universidad de Alcalá, Facultad de Enfermería y Fisioterapia, Grupo de Investigación en Fisioterapia y Dolor, Alcalá de Henares 28801, Spain.
Interdisciplinary Research Group on Musculoskeletal Disorders, Madrid 28014, Spain.
Aging (Albany NY). 2025 May 21;17(5):1328-1339. doi: 10.18632/aging.206254.
This study aims to investigate the relationship between muscle activation variables assessed via ultrasound and the comprehensive assessment of geriatric patients, as well as to analyze ultrasound images to determine their correlation with morbimortality factors in frail patients.
The present cohort study will be conducted in 500 older adults diagnosed with frailty. A multicenter study will be conducted among the day care centers and nursing homes. This will be achieved through the evaluation of frail older adults via instrumental and functional tests, along with specific ultrasound images to study sarcopenia and nutrition, followed by a detailed analysis of the correlation between all collected variables.
This study aims to investigate the correlation between ultrasound-assessed muscle activation variables and the overall health of geriatric patients. It addresses the limitations of previous research by including a large sample size of 500 patients and measuring various muscle parameters beyond thickness. Additionally, it aims to analyze ultrasound images to identify markers associated with higher risk of complications in frail patients. The study involves frail older adults undergoing functional tests and specific ultrasound examinations. A comprehensive analysis of functional, ultrasound, and nutritional variables will be conducted to understand their correlation with overall health and risk of complications in frail older patients.
The study was approved by the Research Ethics Committee of the Hospital Universitario Puerta de Hierro, Madrid, Spain (Act nº 18/2023). In addition, the study was registered with https://clinicaltrials.gov/ (NCT06218121).
本研究旨在探讨通过超声评估的肌肉激活变量与老年患者综合评估之间的关系，并分析超声图像以确定其与虚弱患者死亡风险因素的相关性。
本队列研究将在500名被诊断为虚弱的老年人中进行。将在日间护理中心和养老院开展一项多中心研究。这将通过对虚弱老年人进行仪器和功能测试以及特定超声图像来评估肌肉减少症和营养状况来实现，随后对所有收集到的变量之间的相关性进行详细分析。
本研究旨在探讨超声评估的肌肉激活变量与老年患者整体健康之间的相关性。它通过纳入500名患者的大样本量并测量厚度以外的各种肌肉参数来解决先前研究的局限性。此外，它旨在分析超声图像以识别与虚弱患者并发症高风险相关的标志物。该研究涉及接受功能测试和特定超声检查的虚弱老年人。将对功能、超声和营养变量进行综合分析，以了解它们与虚弱老年患者整体健康和并发症风险的相关性。
该研究已获得西班牙马德里普埃尔塔德耶罗大学医院研究伦理委员会的批准（第18/2023号法案）。此外，该研究已在https://clinicaltrials.gov/注册（NCT06218121）。
