Loayza Alex, Lewis Alston, Trivedi Rupal H, Gouvea Larissa, Bowsher James D, Wolf Bethany, Hernandez Vanessa, Peterseim M Millicent W
Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina.
Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina.
J AAPOS. 2025 Jun;29(3):104228. doi: 10.1016/j.jaapos.2025.104228. Epub 2025 May 23.
To evaluate the QuickSee platform's ability to detect and measure refractive error relative to gold standard cycloplegic retinoscopy in a pediatric population in a clinical setting.
Children 3-17 years of age underwent visual acuity screening, autorefraction by the QuickSee (QS) or QuickSee Free (QSF), and complete ophthalmic examination, including cycloplegic retinoscopy and refraction. The agreement of the results was evaluated by Bland-Altman plots. Sensitivity and specificity for detecting myopia, anisometropia, and astigmatism were calculated based on modified Orinda and AAPOS 2021 guidelines. The overall accuracy of detecting refractive error was analyzed with receiver operating characteristic curves.
A total of 157 children (mean age, 7.58 ± 2.62 years) underwent autorefraction by the QS system (QS/QSF), with a testability of 98.1%. Moderate-to-good agreement was seen in spherical equivalent (SE) and J between the QS system and retinoscopy. The slightly negative bias for SE and J suggests underestimation of QS measurements relative to retinoscopy. The area under curve was >0.9 for all definitions of hyperopia, myopia, and astigmatism. The QS system had sensitivities and specificities >0.8 for hyperopia, myopia, and astigmatism at all levels of refractive error considered. Using modified Orinda and AAPOS 2021 referral guidelines, the QS system demonstrated sensitivities of 89.2% and 94.4%, and specificities of 56.5% and 68.6%, respectively.
In our pediatric study cohort, the QS system effectively identified significant refractive error.
评估QuickSee平台在临床环境中检测和测量儿童屈光不正的能力，并与金标准睫状肌麻痹验光法进行对比。
对3至17岁的儿童进行视力筛查，使用QuickSee（QS）或QuickSee Free（QSF）进行自动验光，并进行全面的眼科检查，包括睫状肌麻痹验光和验光。结果的一致性通过Bland-Altman图进行评估。根据修改后的奥林达和美国儿科学会眼科学分会（AAPOS）2021年指南计算检测近视、屈光参差和散光的敏感性和特异性。使用受试者工作特征曲线分析检测屈光不正的总体准确性。
共有157名儿童（平均年龄7.58±2.62岁）通过QS系统（QS/QSF）进行了自动验光，可测试性为98.1%。QS系统与验光之间在等效球镜度（SE）和J值上呈现出中度至良好的一致性。SE和J值的轻微负偏差表明，相对于验光，QS测量值被低估。对于所有远视、近视和散光的定义，曲线下面积均>0.9。在所有考虑的屈光不正水平上，QS系统对远视、近视和散光的敏感性和特异性均>0.8。根据修改后的奥林达和AAPOS 2021转诊指南，QS系统的敏感性分别为89.2%和94.4%，特异性分别为56.5%和68.6%。
在我们的儿童研究队列中，QS系统有效地识别了显著的屈光不正。
