Saha Bhawesh C, Kumari Rashmi, Onkar Abhishek, Das Sujit, Pal Tajinder
Department of Ophthalmology, All India Institute of Medical Sciences, Patna, Bihar, India.
Department of Ophthalmology, All India Institute of Medical Sciences, Deoghar, Jharkhand, India.
J Curr Glaucoma Pract. 2025 Jan-Mar;19(1):38-49. doi: 10.5005/jp-journals-10078-1461. Epub 2025 Mar 24.
Glaucoma, a multifactorial disease, currently leads the causes of irreversible blindness globally, with complex underlying pathophysiology. For a long time, decreasing intraocular pressure (IOP) has remained the desired primary outcome for each modality of glaucoma management-medical, laser, or surgical. However, the understanding of non-IOP-dependent mechanisms and the identification of additional risk factors affecting optic nerve health have extended the range of preventive and therapeutic options for tackling glaucoma in a more holistic manner. Adopting a healthy lifestyle has been the key to managing all chronic diseases, especially cardiovascular disorders and diabetes, with proven benefits in significantly reducing their incidence and severity. Glaucoma is recognized as a chronic degenerative ailment of the second cranial nerve, and lately, there has been a tremendous upsurge in the subject to evaluate the potential role of lifestyle factors like diet, nutrition, exercises, sleep postures, and smoking in relation to the health of the optic nerve. Existing evidence suggests that some modifications in lifestyle have positive impact in preventing development and retarding its progression, although some findings are conflicting. This write-up aims to furnish a comprehensive overview of the same by analyzing existing evidence and summarizing the repercussions of different lifestyle factors-namely diet and nutritional supplements or exercises-on IOP or the perfusion pressure of the eye, which ultimately leads to retinal ganglion cell loss and optic neuropathy. Knowledge of their putative role as preventive or supportive medicine in glaucoma management can empower both patients and glaucoma specialists in mitigating the agony of the disease affecting the quality of life.
Saha BC, Kumari R, Onkar A, . Lifestyle Modification as Complementary Medicine in Glaucoma Management. J Curr Glaucoma Pract 2025;19(1):38-49.
青光眼是一种多因素疾病,目前在全球不可逆失明原因中居首位,其潜在病理生理学复杂。长期以来,降低眼压一直是青光眼各种治疗方式(药物、激光或手术)所期望达到的主要治疗效果。然而,对非眼压依赖机制的认识以及对影响视神经健康的其他危险因素的识别,扩展了以更全面方式应对青光眼的预防和治疗选择范围。采取健康的生活方式一直是管理所有慢性疾病的关键,尤其是心血管疾病和糖尿病,事实证明这在显著降低其发病率和严重程度方面具有益处。青光眼被认为是第二颅神经的慢性退行性疾病,最近,人们对饮食、营养、运动、睡眠姿势和吸烟等生活方式因素对视神经健康的潜在作用进行评估的研究大幅增加。现有证据表明,尽管有些研究结果相互矛盾,但生活方式的一些改变对预防青光眼的发生和延缓其进展具有积极影响。本文旨在通过分析现有证据并总结不同生活方式因素(即饮食和营养补充剂或运动)对眼压或眼部灌注压的影响,从而对视神经节细胞丢失和视神经病变的影响进行全面概述。了解它们在青光眼管理中作为预防或辅助药物的假定作用,可以使患者和青光眼专家都有能力减轻这种影响生活质量的疾病所带来的痛苦。
萨哈·B·C、库马里·R、翁卡尔·A等。生活方式改变作为青光眼管理的补充医学。《当代青光眼实践杂志》2025年;19(1):38 - 49。