Poli Muriel
Department of Ophthalmology, Centre Ophtalmologique Pôle Vision, Clinique du Val d'Ouest, Ecully, France.
J Curr Glaucoma Pract. 2025 Jan-Mar;19(1):55-63. doi: 10.5005/jp-journals-10078-1470. Epub 2025 Mar 24.
To compare real-world outcomes of Henson 9000 perimeter and Humphrey field analyzer (HFA) in glaucoma patients.
This retrospective study recruited patients diagnosed with glaucoma who underwent Swedish interactive thresholding algorithm (SITA) Standard perimetry (HFA, Carl Zeiss Meditec), followed by Zippy Adaptive Threshold Algorithm (ZATA) Standard perimetry (Henson 9000, Topcon Healthcare). Test durations, global indices, and reliability indices were compared. A subgroup analysis was done for patients classed as early [mean deviation (MD) ≥ -6 dB] and moderate-severe (MD < -6 dB) glaucoma. Fatigue-adjusted subgroup analysis was done, including right eyes only.
76 eyes of 44 patients were included. Henson 9000 results were within normal reliability limits, although they showed higher false positives (FP) (by 6.79%; < 0.001), false negatives (FN) (by 23.17%; < 0.001), and fixation losses (FL) (by 9.5%; = 0.018). Overall, Henson tests showed a slight increase in MD (+1.01 dB, = 0.004), with no significant differences in duration ( = 0.083) or pattern standard deviation (PSD) ( = 0.742). A strong positive correlation between devices was observed for MD ( = 0.903; < 0.001) and PSD ( = 0.850; < 0.001). In early glaucoma ( = 57), mean Henson test duration was shorter by 1.06 minutes ( < 0.001) with no significant difference in MD results ( = 0.083). In all right eyes ( = 38), there were no statistically significant differences in mean duration, MD, and PSD between both devices ( = 0.369, 0.168, 0.537, respectively).
Outcomes with the Henson 9000 were reliable, with measured global indices strongly correlated with HFA results. In early glaucoma, outcomes were comparable to HFA with shorter tests, suggesting the potential of the Henson 9000 as a screening tool for early glaucoma.
Poli M. Comparison of the Real-world Performance of Henson 9000 Perimeter and Humphrey Field Analyzer in Glaucoma Patients. J Curr Glaucoma Pract 2025;19(1):55-63.
比较青光眼患者中Henson 9000视野计与 Humphrey 视野分析仪（HFA）的实际应用效果。
本回顾性研究纳入了被诊断为青光眼且接受过瑞典交互式阈值算法（SITA）标准视野检查（HFA，卡尔蔡司医疗），随后又接受了快速自适应阈值算法（ZATA）标准视野检查（Henson 9000，拓普康医疗）的患者。比较了检查时长、整体指标和可靠性指标。对被分类为早期[平均偏差（MD）≥ -6 dB]和中重度（MD < -6 dB）青光眼的患者进行了亚组分析。进行了疲劳调整亚组分析，仅包括右眼。
纳入了44例患者的76只眼。Henson 9000的检查结果在正常可靠性范围内，尽管其假阳性（FP）率较高（高6.79%；< 0.001）、假阴性（FN）率较高（高23.17%；< 0.001）以及固视丢失（FL）率较高（高9.5%；= 0.018）。总体而言，Henson检查显示MD略有增加（+1.01 dB，= 0.004），检查时长（= 0.083）或模式标准差（PSD）（= 0.742）无显著差异。观察到两种设备在MD（= 0.903；< 0.001）和PSD（= 0.850；< 0.001）方面存在强正相关。在早期青光眼患者（= 57）中，Henson检查的平均时长缩短了1.06分钟（< 0.001），MD结果无显著差异（= 0.083）。在所有右眼（= 38）中，两种设备在平均时长、MD和PSD方面均无统计学显著差异（分别为= 0.369、0.168、0.537）。
Henson 9000的检查结果可靠，所测量的整体指标与HFA结果高度相关。在早期青光眼中，其检查结果与HFA相当且检查时间更短,表明Henson 9000作为早期青光眼筛查工具的潜力。
Poli M. Comparison of the Real-world Performance of Henson 9000 Perimeter and Humphrey Field Analyzer in Glaucoma Patients. J Curr Glaucoma Pract 2025;19(1):55 - 63.
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