Parvin S D, Evans D H, Bell P R
Br J Surg. 1985 Sep;72(9):751-3. doi: 10.1002/bjs.1800720928.
Thirty-seven patients undergoing femoropopliteal, fifteen undergoing femorodistal reconstruction and seven below knee amputees were subjected to prospective measurement of peripheral resistance. Resistance was significantly higher in the amputation and femorodistal groups than in the femoropopliteal group (P less than 0.03 and P less than 0.005 at 76 ml/min). In the femoropopliteal group patients with three vessel runoff had a significantly lower resistance than those with two or single vessel runoff (P less than 0.01). In the femoropopliteal group resistance of patent grafts at four months was significantly less than thrombosed grafts (P less than 0.006). Patients with a resistance less than 1200 mPRU had a significantly better patency than those in whom the resistance was greater than 1200 mPRU (P less than 0.05). Taking all the failed grafts there was a significant correlation between graft patency and resistance (P less than 0.003). Resistance measurement has been shown to correlate with the severity of the disease, with runoff defined radiographically and with graft patency. In a simplified form it may prove a useful adjunct to other methods of assessment in patients with distal disease.
37例行股腘动脉重建术的患者、15例行股腘远端重建术的患者以及7例膝下截肢患者接受了外周阻力的前瞻性测量。截肢组和股腘远端组的阻力显著高于股腘动脉组（在76毫升/分钟时，P<0.03和P<0.005）。在股腘动脉组中，有三支血管流出道的患者阻力显著低于有两支或单支血管流出道的患者（P<0.01）。在股腘动脉组中，四个月时通畅移植物的阻力显著低于血栓形成移植物（P<0.006）。阻力小于1200 mPRU的患者通畅率显著高于阻力大于1200 mPRU的患者（P<0.05）。综合所有失败的移植物来看，移植物通畅率与阻力之间存在显著相关性（P<0.003）。已证明阻力测量与疾病严重程度、影像学定义的流出道以及移植物通畅率相关。以简化形式，它可能被证明是对远端疾病患者其他评估方法的有用辅助手段。
