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人工智能决策支持对临床专家解读造釉细胞瘤型颅咽管瘤影像学表现的影响

Impact of AI Decision Support on Clinical Experts' Radiographic Interpretation of Adamantinomatous Craniopharyngioma.

作者信息

Prince Eric W, Mirsky David M, Hankinson Todd C, Görg Carsten

机构信息

University of Colorado Anschutz Medical Campus, Aurora, CO.

Colorado School of Public Health, Aurora, CO.

出版信息

AMIA Annu Symp Proc. 2025 May 22;2024:930-939. eCollection 2024.

PMID:40417524
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12099361/
Abstract

This research explores the integration of Artificial Intelligence (AI) into clinical decision-making in pediatric brain tumor care, specifically Adamantinomatous Craniopharyngioma (ACP). We present a user-centered design approach to introducing AI tools into clinical workflows to support decision-making in managing Central Nervous System tumors. We conducted a controlled experiment with six clinical experts to explore the hypothesis that AI integrated into clinical contexts can improve the radiographic interpretation of ACP. We found that AI assistance reduced task difficulty and enhanced clinical efficiency; we also discovered variations in user behavior during the annotation process. We identified multiple challenges, including the interpretive complexity of radiographic images and increased disagreements among clinicians when AI was employed. Our study underscores the importance of a nuanced understanding of clinician experiences for successful AI integration into a high-stakes clinical workflow.

摘要

本研究探讨了将人工智能(AI)整合到小儿脑肿瘤护理,特别是成釉细胞瘤型颅咽管瘤(ACP)的临床决策中。我们提出了一种以用户为中心的设计方法,将人工智能工具引入临床工作流程,以支持中枢神经系统肿瘤管理中的决策。我们对六位临床专家进行了一项对照实验,以探讨将人工智能整合到临床环境中可以改善ACP影像学解释的假设。我们发现,人工智能辅助降低了任务难度,提高了临床效率;我们还发现了注释过程中用户行为的差异。我们确定了多个挑战,包括影像学图像的解释复杂性以及使用人工智能时临床医生之间分歧的增加。我们的研究强调了对临床医生经验进行细致入微的理解对于成功将人工智能整合到高风险临床工作流程中的重要性。

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Impact of AI Decision Support on Clinical Experts' Radiographic Interpretation of Adamantinomatous Craniopharyngioma.人工智能决策支持对临床专家解读造釉细胞瘤型颅咽管瘤影像学表现的影响
AMIA Annu Symp Proc. 2025 May 22;2024:930-939. eCollection 2024.
2
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本文引用的文献

1
The Iterative Design Process of an Explainable AI Application for Non-Invasive Diagnosis of CNS Tumors: A User-Centered Approach.一种用于中枢神经系统肿瘤无创诊断的可解释人工智能应用的迭代设计过程:以用户为中心的方法。
IEEE Workshop Vis Anal Healthc. 2023 Oct;2023:7-13. doi: 10.1109/vahc60858.2023.00008. Epub 2023 Dec 18.
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EASL: A Framework for Designing, Implementing, and Evaluating ML Solutions in Clinical Healthcare Settings.欧洲肝脏研究学会:临床医疗环境中设计、实施和评估机器学习解决方案的框架。
Proc Mach Learn Res. 2023 Aug;219:612-630.
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Artificial Intelligence in the Future Landscape of Pediatric Neuroradiology: Opportunities and Challenges.人工智能在儿科神经放射学的未来图景中:机遇与挑战。
AJNR Am J Neuroradiol. 2024 May 9;45(5):549-553. doi: 10.3174/ajnr.A8086.
4
Radio-pathomic approaches in pediatric neuro-oncology: Opportunities and challenges.儿科神经肿瘤学中的放射组学方法:机遇与挑战。
Neurooncol Adv. 2023 Sep 13;5(1):vdad119. doi: 10.1093/noajnl/vdad119. eCollection 2023 Jan-Dec.
5
Integrative Imaging Informatics for Cancer Research: Workflow Automation for Neuro-Oncology (I3CR-WANO).癌症研究的整合影像学信息学:神经肿瘤学工作流程自动化 (I3CR-WANO)。
JCO Clin Cancer Inform. 2023 May;7:e2200177. doi: 10.1200/CCI.22.00177.
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Contemporary Biological Insights and Clinical Management of Craniopharyngioma.颅咽管瘤的当代生物学见解与临床管理
Endocr Rev. 2023 May 8;44(3):518-538. doi: 10.1210/endrev/bnac035.
7
Explainable medical imaging AI needs human-centered design: guidelines and evidence from a systematic review.可解释的医学影像人工智能需要以人类为中心的设计:系统评价的指南与证据
NPJ Digit Med. 2022 Oct 19;5(1):156. doi: 10.1038/s41746-022-00699-2.
8
Explainability of deep neural networks for MRI analysis of brain tumors.深度神经网络在脑肿瘤 MRI 分析中的可解释性。
Int J Comput Assist Radiol Surg. 2022 Sep;17(9):1673-1683. doi: 10.1007/s11548-022-02619-x. Epub 2022 Apr 23.
9
Aggressive pituitary tumours and pituitary carcinomas.侵袭性垂体肿瘤和垂体癌。
Nat Rev Endocrinol. 2021 Nov;17(11):671-684. doi: 10.1038/s41574-021-00550-w. Epub 2021 Sep 7.
10
Pediatric brain tumors: the era of molecular diagnostics, targeted and immune-based therapeutics, and a focus on long term neurologic sequelae.儿科脑肿瘤:分子诊断、靶向和免疫治疗时代,以及对长期神经后遗症的关注。
Curr Probl Cancer. 2021 Aug;45(4):100777. doi: 10.1016/j.currproblcancer.2021.100777. Epub 2021 Jul 16.