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约旦大学医学和牙科专业学生中普萘洛尔的不当使用情况:横断面研究

Inappropriate use of propranolol among medical and dental students at the University of Jordan: cross-sectional study.

作者信息

Taha Hana, Awamleh Suhib, Al Tayyeb AbdelRahman, Samhouri Salwa, Abbasi Yousef, Alwaked Lujaien, El Jaber Aya, Massad Raseel, Alkhaldi Sireen M

机构信息

Department of Family and Community Medicine, School of Medicine, University of Jordan, Amman, Jordan.

Department of Neurobiology, Care Science and Society, Karolinska Institutet, Stockholm, Sweden.

出版信息

Front Med (Lausanne). 2025 May 9;12:1586068. doi: 10.3389/fmed.2025.1586068. eCollection 2025.

Abstract

AIM

This paper aimed to investigate the prevalence of beta-blocker inappropriate use specifically propranolol, among medical and dental students at the University of Jordan. It examined the patterns of Propranolol consumption for stress management including frequency of usage, dosage, side effects experienced as well as the respondents' level of awareness about the risks associated with unsupervised propranolol use.

METHODS

Cross-sectional study conducted at the University of Jordan in December 2024 and recruited 584 students (418 Medicine, 166 Dentistry). The data were analyzed using SPSS (version 27). Descriptive statistics were used to describe the sample, Pearson's chi-squared test, fisher's exact test, independent samples -test and binary logistic regression model were used to identify the predictors of propranolol use. Statistical significance was set at a -value ≤ 0.05.

RESULTS

Among the participants, 9.9% of the students reported using propranolol and 44% of the users learned about the medication through the recommendation of their friends and peers. Even though most students (74.1%) were aware of the potential risks of unsupervised propranolol use, still, 58.6% of the users took it without a prescription. The most common reasons for using propranolol were anxiety management (65.5%) and exam stress (60.3%). Most propranolol users (60.3%) noticed improvement in their academic performance and 36.2% of them experienced side effects such as dizziness and fatigue.

CONCLUSION

Self-medication with propranolol among medical students to deal with academic anxiety carries serious risks. The findings of this research necessitate covering the potential hazards of self-prescription with beta-blockers within the curriculum of undergraduate medical and dental students. Moreover, there is a need for implementing student psychosocial support programs to improve their approach to managing stress and academic pressure.

摘要

目的

本文旨在调查约旦大学医学和牙科专业学生中β受体阻滞剂(特别是普萘洛尔)的不当使用情况。研究考察了普萘洛尔用于压力管理的消费模式,包括使用频率、剂量、所经历的副作用,以及受访者对无监督使用普萘洛尔相关风险的认知水平。

方法

2024年12月在约旦大学进行了一项横断面研究,招募了584名学生(418名医学专业,166名牙科专业)。使用SPSS(版本27)对数据进行分析。描述性统计用于描述样本,Pearson卡方检验、Fisher精确检验、独立样本t检验和二元逻辑回归模型用于确定普萘洛尔使用的预测因素。统计学显著性设定为P值≤0.05。

结果

在参与者中,9.9%的学生报告使用过普萘洛尔,44%的使用者是通过朋友和同伴的推荐了解到这种药物的。尽管大多数学生(74.1%)意识到无监督使用普萘洛尔的潜在风险,但仍有58.6%的使用者在没有处方的情况下服用。使用普萘洛尔最常见的原因是管理焦虑(65.5%)和考试压力(60.3%)。大多数普萘洛尔使用者(60.3%)注意到学业成绩有所提高,36.2%的使用者经历过头晕和疲劳等副作用。

结论

医学生自行服用普萘洛尔来应对学业焦虑存在严重风险。本研究结果有必要在本科医学和牙科学生的课程中涵盖β受体阻滞剂自我开处方的潜在危害。此外,需要实施学生心理社会支持项目,以改善他们应对压力和学业压力的方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16b9/12098573/bdcf0f03c81d/fmed-12-1586068-g001.jpg

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