Salcedo-Giraldo Jordy, Shi Yi
Children's National Hospital, 111 Michigan Ave NW, Washington, DC, 20010, USA.
George Washington University School of Medicine, Washington, DC, USA.
Pediatr Nephrol. 2025 Nov;40(11):3395-3397. doi: 10.1007/s00467-025-06824-z. Epub 2025 May 26.
Hemorrhagic cystitis secondary to BK virus is often seen in immunocompromised patients, but it is a rare cause of hematuria or hemorrhagic cystitis in immunocompetent children. We report a case of an otherwise healthy 4-year-old female who presented to urgent care for urinary frequency, dysuria, and gross hematuria. The initial hematuria workup, including complements, anti-nuclear antibody, anti-streptolysin O titer, and urine culture, was all negative. However, hematuria persisted for 14 days and further work up showed viral PCRs that were positive for BK virus both in blood and urine.