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经鼻内镜经斜坡入路双侧前内侧岩骨切除术治疗累及岩尖和海绵窦的钙化性蝶岩斜角软骨肉瘤:微创解决方案的技术细节。病例展示

Bilateral anteromedial petrosectomy via endoscopic endonasal transclival approach for calcified sphenopetroclival chondrosarcoma with petrous apices and cavernous sinus involvement: technical nuances of a minimally invasive solution. Illustrative case.

作者信息

Khaleghi Mehdi, Hussain Shahid Adnan, Butler Danner, Dyess Garrett, Noelle Hummel Ursula, Record Barnett Asa, Deep Thakur Jai

机构信息

Department of Neurosurgery, University of South Alabama, Mobile, Alabama.

出版信息

J Neurosurg Case Lessons. 2025 May 26;9(21). doi: 10.3171/CASE25119.

DOI:10.3171/CASE25119
PMID:40418894
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12105591/
Abstract

BACKGROUND

Sphenopetroclival chondrosarcomas (SPCCs) typically present as paramidline lytic tumors. Bilateral disease or calcific degeneration is infrequent but associated with increased surgical morbidity and suboptimal removal when adhering to neurovascular structures. The endoscopic endonasal transclival approach (EETA) effectively accesses the retrocarotid space using angled instruments. The authors present the technical nuances of EETA for a large calcified SPCC with bilateral petrous apex involvement without utilizing a full transpterygoid approach or carotid mobilization.

OBSERVATIONS

A 41-year-old male presented with chronic, nonspecific headaches. CT imaging revealed a large sclerotic-lytic mass in the upper-middle clival area involving both petrous apices. MRI showed anterior pontine compression, bilateral cavernous sinus involvement, and partial encasement of the left cavernous carotid artery (CCA). An EETA with bilateral anteromedial petrosectomy and transcavernous access was performed, and near-total resection was achieved. Histopathology confirmed a grade 1 conventional chondrosarcoma, and the patient subsequently underwent proton beam radiotherapy. Surveillance imaging showed stable residual attached to the left CCA and posterior clinoid process.

LESSONS

EETA offers maximal safe resection of SPCC with bilateral anteromedial petrous apex involvement without the need for complex maneuvers that could jeopardize carotid arteries or vidian nerves. When judiciously planned, low recurrence rates are expected for low-grade tumors. https://thejns.org/doi/10.3171/CASE25119.

摘要

背景

蝶岩斜坡软骨肉瘤(SPCCs)通常表现为中线旁溶骨性肿瘤。双侧病变或钙化退变并不常见,但与手术并发症增加以及在贴近神经血管结构时切除效果欠佳相关。鼻内镜经斜坡入路(EETA)可使用成角器械有效进入颈内动脉后间隙。作者介绍了EETA在处理累及双侧岩尖的大型钙化SPCC时的技术细节,且未采用全翼点入路或颈动脉游离。

观察

一名41岁男性因慢性非特异性头痛就诊。CT成像显示中上斜坡区有一个累及双侧岩尖的大的硬化性溶骨性肿块。MRI显示脑桥前部受压、双侧海绵窦受累以及左侧海绵窦段颈内动脉(CCA)部分包绕。实施了双侧前内侧岩骨次全切除术及经海绵窦入路的EETA,实现了近全切除。组织病理学证实为1级普通型软骨肉瘤,患者随后接受了质子束放疗。随访成像显示残余肿瘤稳定附着于左侧CCA和后床突。

经验教训

EETA能够在不进行可能危及颈动脉或翼管神经的复杂操作的情况下,对累及双侧前内侧岩尖的SPCC进行最大程度的安全切除。经过审慎规划,低级别肿瘤有望获得较低的复发率。https://thejns.org/doi/10.3171/CASE25119。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63a0/12105591/5f9facae61c7/CASE25119_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63a0/12105591/6b59d2050086/CASE25119_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63a0/12105591/3383655f5ce5/CASE25119_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63a0/12105591/5f9facae61c7/CASE25119_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63a0/12105591/6b59d2050086/CASE25119_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63a0/12105591/3383655f5ce5/CASE25119_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63a0/12105591/5f9facae61c7/CASE25119_figure_3.jpg

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