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麻醉兔双侧交感神经刺激期间的持续性脑血管收缩

Sustained cerebral vasoconstriction during bilateral sympathetic stimulation in anesthetized rabbits.

作者信息

Busija D W

出版信息

Brain Res. 1985 Oct 21;345(2):341-4. doi: 10.1016/0006-8993(85)91013-3.

DOI:10.1016/0006-8993(85)91013-3
PMID:4041894
Abstract

Temporal aspects of bilateral sympathetic nerve stimulation on cerebral blood flow (CBF) were examined in anesthetized rabbits (n = 7). CBF ranged from 32 to 50 ml/min per 100 g. Bilateral stimulation reduced blood flow by 17-31% to cerebrum, diencephalon-mesencephalon and cerebellum, and responses were constant between 2 and 6 min of stimulation. Sustained cerebral vasoconstriction is consistent with an important role for sympathetic nerves in the regulation of CBF.

摘要

在麻醉兔(n = 7)中研究了双侧交感神经刺激对脑血流量(CBF)的时间效应。CBF范围为每100克32至50毫升/分钟。双侧刺激使大脑、间脑 - 中脑和小脑的血流量减少17%至31%,并且在刺激2至6分钟之间反应持续稳定。持续的脑血管收缩与交感神经在CBF调节中的重要作用一致。

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