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Gut microbiota: A novel target for sepsis treatment.

作者信息

Shang Weifeng, Zhang Sheng, Yang Lechen, Liu Jiao, Chen Dechang

机构信息

Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

出版信息

Chin Med J (Engl). 2025 Jul 5;138(13):1513-1515. doi: 10.1097/CM9.0000000000003630. Epub 2025 May 26.

DOI:10.1097/CM9.0000000000003630
PMID:40419445
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12233922/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f72/12233922/c98235ddc118/cm9-138-1513-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f72/12233922/c98235ddc118/cm9-138-1513-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f72/12233922/c98235ddc118/cm9-138-1513-g001.jpg

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本文引用的文献

1
The Gut Microbiome in Sepsis: From Dysbiosis to Personalized Therapy.脓毒症中的肠道微生物群：从失调到个性化治疗。
J Clin Med. 2024 Oct 12;13(20):6082. doi: 10.3390/jcm13206082.
2
Genetic causal association between gut microbiota and sepsis: Evidence from a two-sample bidirectional Mendelian randomization analysis.肠道微生物群与脓毒症之间的遗传因果关联：来自两样本双向孟德尔随机化分析的证据。
J Intensive Med. 2024 Jan 8;4(3):362-367. doi: 10.1016/j.jointm.2023.11.006. eCollection 2024 Jul.
3
Gut microbiota and sepsis and sepsis-related death: a Mendelian randomization investigation.
肠道微生物群与脓毒症和脓毒症相关死亡：一项孟德尔随机化研究。
Front Immunol. 2024 Jan 31;15:1266230. doi: 10.3389/fimmu.2024.1266230. eCollection 2024.
4
Gut microbiota composition and changes in patients with sepsis: potential markers for predicting survival.脓毒症患者的肠道微生物组成和变化：预测生存的潜在标志物。
BMC Microbiol. 2024 Feb 1;24(1):45. doi: 10.1186/s12866-024-03188-6.
5
Efficacy of probiotics or synbiotics in critically ill patients: A systematic review and meta-analysis.益生菌或合生菌在危重症患者中的疗效：系统评价和荟萃分析。
Clin Nutr ESPEN. 2024 Feb;59:48-62. doi: 10.1016/j.clnesp.2023.11.003. Epub 2023 Nov 8.
6
Gut Microbiome-Based Therapeutics in Critically Ill Adult Patients-A Narrative Review.基于肠道微生物组的成年危重症患者治疗方法：叙述性综述。
Nutrients. 2023 Nov 9;15(22):4734. doi: 10.3390/nu15224734.
7
Fecal microbiota transplantation and short-chain fatty acids reduce sepsis mortality by remodeling antibiotic-induced gut microbiota disturbances.粪便微生物群移植和短链脂肪酸通过重塑抗生素诱导的肠道微生物群紊乱降低脓毒症死亡率。
Front Immunol. 2023 Jan 11;13:1063543. doi: 10.3389/fimmu.2022.1063543. eCollection 2022.
8
Association Between Selective Decontamination of the Digestive Tract and In-Hospital Mortality in Intensive Care Unit Patients Receiving Mechanical Ventilation: A Systematic Review and Meta-analysis.选择性消化道去污染与机械通气重症监护病房患者院内死亡率的关系：系统评价和荟萃分析。
JAMA. 2022 Nov 15;328(19):1922-1934. doi: 10.1001/jama.2022.19709.
9
Effect of Selective Decontamination of the Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial.选择性消化道去污对机械通气危重症患者住院死亡率的影响：一项随机临床试验。
JAMA. 2022 Nov 15;328(19):1911-1921. doi: 10.1001/jama.2022.17927.
10
The gut-liver axis in sepsis: interaction mechanisms and therapeutic potential.脓毒症的肠-肝轴：相互作用机制和治疗潜力。
Crit Care. 2022 Jul 13;26(1):213. doi: 10.1186/s13054-022-04090-1.