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[嗜酸性食管炎——一种被低估的食物过敏?]

[Eosinophilic esophagitis-an underestimated food allergy?].

作者信息

Hörning A, Madisch A

机构信息

Pädiatrische Gastroenterologie, Hepatologie und Endoskopie, Klinik für Kinder- und Jugendmedizin, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Loschgestr. 15, 91054, Erlangen, Deutschland.

Zentrum Innere Medizin, Diakovere Friederikenstift, Hannover, Deutschland.

出版信息

Dermatologie (Heidelb). 2025 May 26. doi: 10.1007/s00105-025-05513-0.


DOI:10.1007/s00105-025-05513-0
PMID:40419653
Abstract

Eosinophilic oesophagitis (EoE) is a chronic T2-inflammatory disease and can be figuratively referred to as atopic dermatitis of the oesophagus. It is an immune-mediated disease caused by food allergens and is histologically defined by eosinophilic infiltration and clinically characterised by symptoms of oesophageal dysfunction. In addition to reducing the currently still considerable diagnostic latency, the focus is on prioritising existing and new treatment options with the aim of ensuring effective patient care with improved quality of life in the long term.

摘要

嗜酸性食管炎(EoE)是一种慢性2型炎症性疾病,可形象地称为食管特应性皮炎。它是一种由食物过敏原引起的免疫介导性疾病,组织学上以嗜酸性粒细胞浸润为特征,临床上以食管功能障碍症状为特征。除了减少目前仍然相当长的诊断延迟外,重点是对现有和新的治疗方案进行优先排序,以确保长期有效治疗患者并改善生活质量。

相似文献

[1]
[Eosinophilic esophagitis-an underestimated food allergy?].

Dermatologie (Heidelb). 2025-5-26

[2]
Unravelling the pathogenesis of Eosinophilic Esophagitis from genetic predisposition to environmental triggers.

Clin Exp Immunol. 2025-1-21

[3]
IgE-Mediated Food Sensitization, Management Strategies, and Quality of Life in Pediatric Eosinophilic Esophagitis: A Prospective Observational Study.

Nutrients. 2025-6-11

[4]
Eosinophilic Esophagitis due to Aeroallergens: A Systematic Review and Update.

J Investig Allergol Clin Immunol. 2022-12-15

[5]
Eosinophilic esophagitis: updated consensus recommendations for children and adults.

J Allergy Clin Immunol. 2011-4-7

[6]
Outcomes reported in randomized controlled trials for mixed and non-IgE-mediated food allergy: Systematic review.

Clin Exp Allergy. 2023-5

[7]
[Eosinophilic esophagitis].

Inn Med (Heidelb). 2025-2

[8]
Eosinophilic Esophagitis: Prevalence, Diagnosis, and Treatment in Childhood and Adulthood.

Dtsch Arztebl Int. 2025-4-4

[9]
Review article: oesophageal dilation in adults with eosinophilic oesophagitis.

Aliment Pharmacol Ther. 2011-2-14

[10]
Dupilumab in children with eosinophilic esophagitis: a retrospective multicenter study.

BMC Pediatr. 2025-2-5

本文引用的文献

[1]
Eosinophilic Esophagitis: Prevalence, Diagnosis, and Treatment in Childhood and Adulthood.

Dtsch Arztebl Int. 2025-4-4

[2]
Rapid response to dupilumab in an adult patient with eosinophilic esophagitis and allergic asthma.

Allergol Select. 2024-4-5

[3]
Incidence and prevalence of eosinophilic oesophagitis across Europe: A systematic review and meta-analysis.

United European Gastroenterol J. 2024-2

[4]
[Not Available].

Z Gastroenterol. 2023-7

[5]
Efficacy of Elimination Diets in Eosinophilic Esophagitis: A Systematic Review and Meta-analysis.

Clin Gastroenterol Hepatol. 2023-8

[6]
Implementation of a biopsy protocol to improve detection of esophageal eosinophilia: a Danish registry-based study.

Endoscopy. 2021-1

[7]
The genetic etiology of eosinophilic esophagitis.

J Allergy Clin Immunol. 2020-1

[8]
Eosinophilic Esophagitis in Esophageal Atresia.

Front Pediatr. 2019-11-29

[9]
Anxiety and Depression in Eosinophilic Esophagitis: A Scoping Review and Recommendations for Future Research.

J Asthma Allergy. 2019-12-9

[10]
Symptom Burden and Quality of Life Over Time in Pediatric Eosinophilic Esophagitis.

J Pediatr Gastroenterol Nutr. 2019-12

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