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预测黄斑脱离视网膜脱离成功修复术后视力的变化:一项大型英国前瞻性队列研究的结果

Predicting post-surgery change in visual acuity after successful repair of macula-off retinal detachments: findings from a large prospective UK cohort study.

作者信息

Yorston David, Donachie Paul H J, Laidlaw D A, Steel David H, Williamson Tom H

机构信息

Gartnavel Hospital, Glasgow, UK.

Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, GL53 7AN, UK.

出版信息

Eye (Lond). 2025 Aug;39(11):2298-2306. doi: 10.1038/s41433-025-03752-y. Epub 2025 May 26.

Abstract

OBJECTIVE

To identify risk factors affecting the change in visual acuity in successfully re-attached macula-off rhegmatogenous retinal detachment (RD) surgery.

DESIGN

A cohort study, using an online database, of visual outcomes for 2770 macula-off retinal detachments that were successfully re-attached by vitrectomy and internal tamponade. The database included detailed retinal diagrams of each detachment.

MAIN OUTCOME MEASURE

The change in LogMAR visual acuity from pre-operatively to post-operatively.

RESULTS

Male patients accounted for 64.6% of the sample and the median age was 63 years old. The median pre-operative VA was counting fingers (LogMAR 1.98); this improved to 0.30 LogMAR post-operatively. An improvement in VA of ≥0.30 LogMAR was achieved by 88.0% eyes. The change in VA model identified the preoperative VA, patient age, duration of central vision loss, lens status at follow up, extent of detachment, and the number of breaks in the detached retina, as factors influencing the change in VA. The model had an adjusted R of 0.749, and for 75.5% of eyes, the model prediction was within ±0.30 LogMAR of the recorded VA change.

CONCLUSIONS

Greater post-operative visual acuity improvement was more likely in eyes that were pseudophakic at follow up, and had shorter durations of central vision loss. Non modifiable factors associated with greater vision improvement included worse presenting vision, younger age, less extensive detachment and less than three breaks in the detached retina. These results confirm that prompt surgery improves functional outcomes in successfully treated macula off retinal detachments irrespective of presenting visual acuity.

摘要

目的

确定影响成功复位的黄斑脱离孔源性视网膜脱离(RD)手术中视力变化的危险因素。

设计

一项队列研究,使用在线数据库,对2770例通过玻璃体切除术和眼内填充成功复位的黄斑脱离视网膜脱离的视觉结果进行研究。该数据库包括每个脱离的详细视网膜图。

主要观察指标

术前至术后LogMAR视力的变化。

结果

男性患者占样本的64.6%,中位年龄为63岁。术前视力中位数为眼前指数(LogMAR 1.98);术后改善至LogMAR 0.30。88.0%的患眼视力提高≥0.30 LogMAR。视力变化模型确定术前视力、患者年龄、中心视力丧失持续时间、随访时晶状体状态、脱离范围以及脱离视网膜的裂孔数量为影响视力变化的因素。该模型的调整R值为0.749,对于75.5%的患眼,模型预测值与记录的视力变化在±0.30 LogMAR范围内。

结论

随访时为人工晶状体眼且中心视力丧失持续时间较短的患眼术后视力改善更明显。与视力改善更大相关的不可改变因素包括初始视力较差、年龄较轻、脱离范围较小以及脱离视网膜的裂孔少于三个。这些结果证实,无论初始视力如何,及时手术可改善成功治疗的黄斑脱离视网膜脱离的功能结局。

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