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影响黄斑裂孔视网膜脱离修复后视力恢复的因素:来自大型前瞻性英国队列研究的结果。

Factors affecting visual recovery after successful repair of macula-off retinal detachments: findings from a large prospective UK cohort study.

机构信息

Gartnavel Hospital, Glasgow, UK.

Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, GL53 7AN, UK.

出版信息

Eye (Lond). 2021 May;35(5):1431-1439. doi: 10.1038/s41433-020-1021-y. Epub 2020 Jun 24.

Abstract

OBJECTIVE

To identify risk factors affecting visual outcomes in successfully re-attached macula-off rhegmatogenous retinal detachment (RD) surgery.

DESIGN

A prospective study, using online databases, of visual outcomes for 2074 macula-off retinal detachments that were successfully re-attached by vitrectomy and internal tamponade. The database included detailed retinal diagrams of each detachment.

MAIN OUTCOME MEASURE

The probability of achieving a post-operative visual acuity (VA) of ≤0.30 LogMAR (Snellen 6/12 or better).

RESULTS

Male patients accounted for 64.9% of the sample and the median age was 63 years old. The median pre-operative VA was counting fingers (LogMAR 1.98); this improved to 0.41 LogMAR post-operatively. A post-operative VA of ≤0.30 LogMAR was achieved for 1012 (48.8%) eyes and the factors affecting this were the patient age and gender, pre-operative VA, duration of central vision loss, PVR grade, lens status, total RD and the presence of any ocular co-pathology where the model area under the receiver operator curve was 71.6%.

CONCLUSIONS

From the identified risk factors that decrease the probability of achieving a post-operative visual acuity of ≤0.30 LogMAR, the most important modifiable risk factor was the duration of central vision loss. Recent macula-off retinal detachments should be repaired within 72 h of the loss of central vision.

摘要

目的

确定影响成功再附着的黄斑脱离裂孔性视网膜脱离(RD)手术后视力结果的危险因素。

设计

一项前瞻性研究,使用在线数据库,对 2074 例通过玻璃体切除术和内压塞成功再附着的黄斑脱离视网膜脱离进行视力结果的研究。该数据库包括每个脱离的详细视网膜图。

主要观察指标

术后视力(VA)达到≤0.30 LogMAR(Snellen 6/12 或更好)的概率。

结果

男性患者占样本的 64.9%,中位年龄为 63 岁。术前 VA 的中位数为指数(LogMAR 1.98);术后提高到 0.41 LogMAR。1012 只(48.8%)眼术后 VA 达到≤0.30 LogMAR,影响因素为患者年龄和性别、术前 VA、中心视力丧失时间、PVR 分级、晶状体状态、总 RD 和任何眼部合并症,受试者工作特征曲线下的模型面积为 71.6%。

结论

从降低术后视力≤0.30 LogMAR 概率的确定危险因素中,最重要的可改变危险因素是中心视力丧失的时间。最近发生的黄斑脱离视网膜脱离应在中央视力丧失后 72 小时内进行修复。

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