Takeshige Tomohito, Koyama Ryo, Goto Eisuke, Maeyashiki Tatsuo, Okajima Akifumi, Nishioki Toshihiko, Watanabe Junko, Yae Toshifumi, Banno Takamitsu, Kido Kenji, Takahashi Kazuhisa
Department of Respiratory Medicine, Juntendo University Nerima Hospital, 3-1-1, Takanodai, Nerima-ku, Tokyo, 177-8521, Japan.
Department of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, 3-1-3, Hongo, Bunkyo-ku, Tokyo, 113-8431, Japan.
Respir Med Case Rep. 2025 May 2;55:102227. doi: 10.1016/j.rmcr.2025.102227. eCollection 2025.
Idiopathic dendriform pulmonary ossification (IDPO) presents as dendritic ossification of the lungs without a particular cause. IDPO is often diagnosed using surgical biopsy, transbronchial lung biopsy (TBLB), or transbronchial lung cryobiopsy (TBLC). In this case report, we described a 36-year-old male who presented with abnormal chest findings radiographically. TBLB was performed but no diagnosis was made. Instead, IDPO was diagnosed following a surgical biopsy. CT tomography and respiratory function tests showed no progression over the past 3.5 years. However, a nationwide survey in Japan revealed several cases of disease progression. Considering this, careful monitoring of the disease is recommended.