Crooijmans Marjolein E, de Winde Johannes H, Claessen Dennis
Institute of Biology, Leiden University, Sylviusweg, Leiden, Netherlands.
Microbiol Resour Announc. 2025 Jun 12;14(6):e0128324. doi: 10.1128/mra.01283-24. Epub 2025 May 27.
L-forms are bacterial variants capable of proliferating without a cell wall. In this evolution study, we present draft genome sequences of a novel K-12 L-form strain and an evolved variant that exhibits enhanced growth. These draft sequences provide insights into the genetic adaptations associated with cell wall-independent growth.
L型细菌是能够在没有细胞壁的情况下增殖的细菌变体。在这项进化研究中,我们展示了一种新型K-12 L型菌株和一种生长增强的进化变体的基因组草图序列。这些草图序列为与无细胞壁生长相关的遗传适应性提供了见解。