菲律宾啮齿动物自然感染和获得性恙虫病东方体感染中的间接免疫荧光抗体
Indirect immunofluorescence antibodies in natural and acquired Rickettsia tsutsugamushi infections of Philippine rodents.
作者信息
Van Peenen P F, Ho C M, Bourgeois A L
出版信息
Infect Immun. 1977 Mar;15(3):813-6. doi: 10.1128/iai.15.3.813-816.1977.
Abstract
Antibodies against Rickettsia tsutsugamushi detected by the indirect fluorescent-antibody test (IFAT) were present in most rats trapped from a human focus of scrub typhus in the Philippines. Rickettsiae were isolated only from rats with positive IFATs. Naturally acquired antibodies persisted for at least 11 months, and antibodies resulting from experimental infections of rats persisted for at least 7 months. A common Philippine rodent, Rattus mindanensis, tolerated experimental infections with both local and standard Karp strains of R. tsutsugamushi, and such infections always produced a positive IFAT.
摘要
通过间接荧光抗体试验（IFAT）检测到，在菲律宾恙虫病人间疫源地捕获的大多数大鼠体内存在抗恙虫病立克次体抗体。立克次体仅从IFAT呈阳性的大鼠中分离出来。自然获得的抗体至少持续11个月，大鼠实验感染产生的抗体至少持续7个月。菲律宾常见啮齿动物明打威鼠能耐受当地和标准Karp株恙虫病立克次体的实验感染，且此类感染总能产生阳性IFAT结果。
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本文引用的文献
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Proc Soc Exp Biol Med. 1963 Mar;112:568-73. doi: 10.3181/00379727-112-28107.
2
Filter paper collection of blood for use in a screening and diagnostic test for scrub typhus using the IFAT.用滤纸采集血液，用于采用间接荧光抗体试验的恙虫病筛查和诊断检测。
Trans R Soc Trop Med Hyg. 1972;66(4):588-93. doi: 10.1016/0035-9203(72)90304-5.
3
The ecology of chigger-borne rickettsiosis (scrub typhus).恙虫病立克次体病（丛林斑疹伤寒）的生态学
J Med Entomol. 1974 Jul 15;11(3):237-303. doi: 10.1093/jmedent/11.3.237.
4
Scrub typhus antibody in mammals in three habitats in Sabah.沙巴州三个栖息地哺乳动物中的恙虫病抗体。
Southeast Asian J Trop Med Public Health. 1974 Mar;5(1):80-4.
5
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6
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Ann N Y Acad Sci. 1975;266:91-114. doi: 10.1111/j.1749-6632.1975.tb35091.x.
7
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Trans R Soc Trop Med Hyg. 1975;69(1):121-30. doi: 10.1016/0035-9203(75)90021-8.
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