Mehra Rashmi, Ray Arindam, Kumari Amrita, Kaur Amanjot, Hora Rhythm, Quadri Syed F, Koshal Seema Singh, Ray Bodhisatwa, Singh Shyam Kumar, Sultana Abida, Roy Arup Deb
John Snow India, Plot No. 5 & 6, First Floor Allied House, Pocket 10, Sector B, Vasant Kunj, New Delhi, 110070, India, 91 9560213460.
Bill and Melinda Gates Foundation, New Delhi, India.
J Med Internet Res. 2025 May 27;27:e69729. doi: 10.2196/69729.
Human papillomavirus (HPV) is a leading cause of cervical cancer. It has a substantial impact on global public health, with low- and middle-income countries, including India, facing the highest burden. In 2022, India reported 127,526 new cases and 79,906 deaths due to cervical cancer, projected to increase by 61% by 2040. Although the National Technical Advisory Group on Immunization recommended the HPV vaccine for cervical cancer prevention, it is yet to be a part of India's universal immunization program.
This study aims to examine online interest in the HPV vaccine in India from January 2010 to April 2024 using Google Trends.
A cross-sectional analysis of Google Trends data was performed, using the relative search volume to track interest on a scale of 0-100. Trends were analyzed annually using 1-way ANOVA and joinpoint regression to identify significant changes in search behavior related to public health events. Statistical significance was set at P<.05.
The average annual growth in HPV vaccine-related searches was 13.7% (95% CI 7.9%-19.1%), with the highest relative search volume in 2024 (49.5) and the lowest in 2017 (3.38). Spikes in search interest aligned with key events like the 2018 National Technical Advisory Group on Immunization recommendation and the 2022 launch of the indigenous HPV vaccine. The results highlight online search data's value in tracking public interest, which fluctuates in response to health policy changes or developments on social media. In India, targeted digital strategies will be vital for addressing vaccine hesitancy and increasing HPV vaccine uptake.
Google Trends data can inform public health strategies by identifying periods of high interest, aiding in the promotion of HPV vaccination in India.
人乳头瘤病毒（HPV）是宫颈癌的主要病因。它对全球公共卫生有重大影响，包括印度在内的低收入和中等收入国家面临着最高的负担。2022年，印度报告了127526例宫颈癌新发病例和79906例死亡病例，预计到2040年将增加61%。尽管国家免疫技术咨询小组建议使用HPV疫苗预防宫颈癌，但它尚未成为印度通用免疫计划的一部分。
本研究旨在利用谷歌趋势调查2010年1月至2024年4月期间印度对HPV疫苗的在线关注度。
对谷歌趋势数据进行横断面分析，使用相对搜索量在0至100的范围内跟踪关注度。每年使用单因素方差分析和连接点回归分析趋势，以确定与公共卫生事件相关的搜索行为的显著变化。统计学显著性设定为P<0.05。
与HPV疫苗相关搜索的年平均增长率为13.7%（95%CI 7.9%-19.1%），2024年相对搜索量最高（49.5），2017年最低（3.38）。搜索兴趣的峰值与关键事件一致，如2018年国家免疫技术咨询小组的建议和2022年国产HPV疫苗的推出。结果突出了在线搜索数据在跟踪公众兴趣方面的价值，公众兴趣会因卫生政策变化或社交媒体上的发展而波动。在印度，有针对性的数字策略对于解决疫苗犹豫问题和提高HPV疫苗接种率至关重要。
谷歌趋势数据可通过识别高关注度时期为公共卫生策略提供信息，有助于在印度推广HPV疫苗接种。
