Jha Ujjwal Prakash, Narang Subina, Jindal Varsha
Department of Ophthalmology, Government Medical College and Hospital, Chandigarh, Chandigarh, India.
Department of Ophthalmology, Government Medical College and Hospital, Chandigarh, Chandigarh, India
BMJ Case Rep. 2025 May 26;18(5):e255721. doi: 10.1136/bcr-2023-255721.
We present the case of a woman in her late 40s who presented with an iris lesion extending to the ciliary body and mature white cataract with a visual acuity of perception of light in her right eye. The tumour was managed with Bhabha Atomic Research Centre Iodine-125 (BARC I-125) Ocu-Prosta seeds plaque therapy with the amniotic membrane buffer technique. No corneal complications or secondary glaucoma were seen over a 6-month follow-up, and a reduction in tumour size was observed on MRI. Ten months post corneoscleral plaque brachytherapy (PB), the patient underwent phacoemulsification in the same eye and achieved a best corrected visual acuity of 20/40. This case highlights the use of cost-effective indigenous I-125 Ocu-Prosta seeds with amniotic membrane in the successful management of iridociliary melanoma, which has not been reported so far.
我们报告了一例40多岁晚期女性患者的病例，该患者右眼出现虹膜病变并累及睫状体，同时伴有成熟的白色白内障，视力仅为光感。该肿瘤采用了巴布哈原子研究中心碘-125（BARC I-125）眼用前列腺癌种子源敷贴疗法及羊膜缓冲技术进行治疗。在6个月的随访中未发现角膜并发症或继发性青光眼，且MRI检查显示肿瘤大小有所减小。角膜巩膜敷贴近距离放射治疗（PB）10个月后，该患者在同一只眼睛接受了超声乳化手术，最佳矫正视力达到了20/40。本病例突出了使用具有成本效益的国产I-125眼用前列腺癌种子源及羊膜成功治疗虹膜睫状体黑色素瘤的方法，此前尚未有相关报道。
