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Patient-centered integration of tumor and germline genetic results can improve cancer care.

作者信息

Church Alanna J, Bhattacharyya Oindrila, Culver Julie O, Amzaleg Yonatan, Linnenbringer Erin, Smart Maeve, Ip-Toma Christina, Rivera Adan Reinosa, Davis Bethany, Ricker Charité, Lenz Heinz-Josef, Gray Stacy W, Hampel Heather, Craig David W

机构信息

Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Department of Biomedical Informatics, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.

出版信息

Nat Med. 2025 May 27. doi: 10.1038/s41591-025-03686-8.

DOI:10.1038/s41591-025-03686-8
PMID:40425841
Abstract
摘要

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本文引用的文献

1
The 21st Century Cures Act: Inpatient Clinician Perceptions of Changes to Information Sharing at an Academic Medical Center.《21世纪治愈法案》：学术医疗中心住院医师对信息共享变化的看法。
Cureus. 2023 Jun 9;15(6):e40184. doi: 10.7759/cureus.40184. eCollection 2023 Jun.
2
Promoting patient engagement in cancer genomics research programs: An environmental scan.促进患者参与癌症基因组学研究项目：一项环境扫描。
Front Genet. 2023 Jan 18;14:1053613. doi: 10.3389/fgene.2023.1053613. eCollection 2023.
3
Barriers, interventions, and recommendations: Improving the genetic testing landscape.
障碍、干预措施及建议：改善基因检测现状
Front Digit Health. 2022 Nov 1;4:961128. doi: 10.3389/fdgth.2022.961128. eCollection 2022.
4
Recall of Genomic Testing Results Among Patients with Cancer.癌症患者的基因组检测结果召回。
Oncologist. 2021 Dec;26(12):e2302-e2305. doi: 10.1002/onco.13928. Epub 2021 Aug 26.
5
A survey assessing adoption of the ACMG-AMP guidelines for interpreting sequence variants and identification of areas for continued improvement.一项评估采用美国医学遗传学与基因组学学会-美国病理学家协会（ACMG-AMP）解读序列变异指南及确定持续改进领域情况的调查。
Genet Med. 2019 Aug;21(8):1699-1701. doi: 10.1038/s41436-018-0432-7. Epub 2019 Jan 23.
6
Physicians' attitudes about multiplex tumor genomic testing.医生对肿瘤基因多重检测的态度。
J Clin Oncol. 2014 May 1;32(13):1317-23. doi: 10.1200/JCO.2013.52.4298. Epub 2014 Mar 24.
7
The Havasupai Indian tribe case--lessons for research involving stored biologic samples.哈瓦苏派印第安部落案——涉及储存生物样本研究的教训
N Engl J Med. 2010 Jul 15;363(3):204-7. doi: 10.1056/NEJMp1005203. Epub 2010 Jun 9.