Hayakawa R, Matsunaga K, Kojima S, Kaniwa M, Nakamura A
Contact Dermatitis. 1985 Jul;13(1):20-5. doi: 10.1111/j.1600-0536.1985.tb02486.x.
Naphthol AS is a coupling agent of cotton dyeing. 2 elderly women with hyperpigmentation of the neck and limbs are described. Both felt itching on the neck, forearms, and lower extremities and noted hyperpigmentation a month later. Both had worn cotton flannel nightdresses in winter. Patch testing with cotton flannel and methanol extracts were positive, but after estraction with methanol, the residual flannel did not react. The methanol extracts of cotton flannel, were analysed. The patients were tested with 5 extracted components; Naphthol AS was found to be the causative agent.
萘酚AS是一种棉织物染色偶联剂。本文描述了2例颈部和四肢色素沉着的老年女性。两人均感到颈部、前臂和下肢瘙痒，并在一个月后发现色素沉着。两人在冬季都穿着棉法兰绒睡裙。用棉法兰绒和甲醇提取物进行斑贴试验呈阳性，但用甲醇提取后，残留的法兰绒无反应。对棉法兰绒的甲醇提取物进行了分析。对患者用5种提取物成分进行检测；发现萘酚AS是致病因素。
