小白菊内酯所致皮炎的治疗。

Treatment of dermatitis from parthenin.

作者信息

Picman J, Picman A K

出版信息

Contact Dermatitis. 1985 Jul;13(1):9-13. doi: 10.1111/j.1600-0536.1985.tb02484.x.

DOI:10.1111/j.1600-0536.1985.tb02484.x

Abstract

Composites and some other plants containing sesquiterpene lactones, frequently cause allergic contact dermatitis in man. No treatment is available to control this disease successfully. We have used an amino acid, cysteine, to treat allergic contact dermatitis in guinea pigs sensitized to parthenin, a major sesquiterpene lactone of an allergenic weed, Parthenium hysterophorus L. Cysteine treatment of the allergic reaction induced by parthenin resulted in (a) reduced time of recovery and (b) reduced intensity of the skin reaction.

摘要

含有倍半萜内酯的菊科植物及其他一些植物，常常会引发人类过敏性接触性皮炎。目前尚无有效的治疗方法来成功控制这种疾病。我们使用了一种氨基酸——半胱氨酸，来治疗对银胶菊素过敏的豚鼠的过敏性接触性皮炎。银胶菊素是一种具有致敏性的杂草——银胶菊（Parthenium hysterophorus L.）中的主要倍半萜内酯。用半胱氨酸治疗由银胶菊素引发的过敏反应，结果是：（a）恢复时间缩短；（b）皮肤反应强度降低。